Yoshidome Hiroyuki, Miyazaki Masaru
Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
Nihon Geka Gakkai Zasshi. 2013 Jan;114(1):39-43.
Hepatic resection is recognized as a potentially curative treatment for colorectal liver metastases. Recent progress in chemotherapy and molecular target agents has made initially unresectable colorectal liver metastases converted to resectable and may prolong survival. The definition of unresectable colorectal liver metastases was because of the lack of the future remnant liver volume due to multiple bilobar metastases. The two-stage hepatectomy combined with portal vein embolization may contribute to treatment for such multiple bilobar metastases. We describe an advantage and adverse effect of two-stage hepatectomy on treatment for multiple bilobar colorectal liver metastases.
肝切除术被认为是治疗结直肠癌肝转移的一种潜在治愈性方法。化疗和分子靶向药物的最新进展已使最初无法切除的结直肠癌肝转移转变为可切除，并可能延长生存期。无法切除的结直肠癌肝转移的定义是由于多叶转移导致未来残余肝体积不足。两阶段肝切除术联合门静脉栓塞术可能有助于治疗此类多叶转移。我们描述了两阶段肝切除术在治疗多叶结直肠癌肝转移中的优势和不良反应。
