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胺碘酮肺毒性的自发消退

Spontaneous regression of amiodarone pulmonary toxicity.

作者信息

Fraioli P, Barberis M, Montemurro L

机构信息

Pathology Dept, Niguarda Hospital, Milan, Italy.

出版信息

Sarcoidosis. 1990 Mar;7(1):58-62.

PMID:2345820
Abstract

Two patients with Amiodarone-induced interstitial lung disease are described. The pulmonary lung biopsy in one of them, as well as Chest X ray, BAL cellularity and pulmonary function data in both, are in agreement with the reports from the literature, while Ga lung scan was negative in one of the two, and positive in the other one. In both, a total resolution was seen six and four months respectively after discontinuation of Amiodarone therapy. Corticosteroid therapy could be advisable only when no spontaneous resolution occurs after tapering the drug.

摘要

描述了两名胺碘酮所致间质性肺病患者。其中一名患者的肺活检,以及两人的胸部X光、支气管肺泡灌洗细胞计数和肺功能数据均与文献报道相符,而镓肺扫描在两人中一人为阴性,另一人为阳性。两人在停用胺碘酮治疗后分别于6个月和4个月时完全康复。仅在逐渐减少药物用量后无自发缓解时,才建议使用皮质类固醇治疗。

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