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胺碘酮肺毒性的自发消退

Spontaneous regression of amiodarone pulmonary toxicity.

作者信息

Fraioli P, Barberis M, Montemurro L

机构信息

Pathology Dept, Niguarda Hospital, Milan, Italy.

出版信息

Sarcoidosis. 1990 Mar;7(1):58-62.

PMID:2345820
Abstract

Two patients with Amiodarone-induced interstitial lung disease are described. The pulmonary lung biopsy in one of them, as well as Chest X ray, BAL cellularity and pulmonary function data in both, are in agreement with the reports from the literature, while Ga lung scan was negative in one of the two, and positive in the other one. In both, a total resolution was seen six and four months respectively after discontinuation of Amiodarone therapy. Corticosteroid therapy could be advisable only when no spontaneous resolution occurs after tapering the drug.

摘要

描述了两名胺碘酮所致间质性肺病患者。其中一名患者的肺活检,以及两人的胸部X光、支气管肺泡灌洗细胞计数和肺功能数据均与文献报道相符,而镓肺扫描在两人中一人为阴性,另一人为阳性。两人在停用胺碘酮治疗后分别于6个月和4个月时完全康复。仅在逐渐减少药物用量后无自发缓解时,才建议使用皮质类固醇治疗。

相似文献

1
Spontaneous regression of amiodarone pulmonary toxicity.胺碘酮肺毒性的自发消退
Sarcoidosis. 1990 Mar;7(1):58-62.
2
Amiodarone-induced pulmonary toxicity.胺碘酮诱发的肺毒性。
J Can Assoc Radiol. 1984 Jun;35(2):195-8.
3
[The pulmonary toxicity of amiodarone: six-case report].[胺碘酮的肺毒性:六例报告]
Zhonghua Xin Xue Guan Bing Za Zhi. 2005 Jan;33(1):66-8.
4
Pulmonary gallium-67 uptake in amiodarone pneumonitis.
J Nucl Med. 1984 Feb;25(2):211-3.
5
[Pulmonary toxicity due to amiodarone].[胺碘酮所致肺毒性]
Cardiologia. 1993 Feb;38(2):129-32.
6
[Recurrent alveolitis caused by amiodarone].[胺碘酮所致复发性肺泡炎]
G Ital Cardiol. 1986 Feb;16(2):177-80.
7
[Amiodarone and diffuse alveolar-interstitial pulmonary infiltrate. A case report].[胺碘酮与弥漫性肺泡-间质肺浸润。一例报告]
Arq Bras Cardiol. 1984 Mar;42(3):213-6.
8
[Amiodarone-induced pulmonary fibrosis].
Orv Hetil. 1996 Aug 11;137(32):1759-62.
9
[Pulmonary toxicity of amiodarone].[胺碘酮的肺毒性]
Rev Med Brux. 1987 Oct;8(8):399-401.
10
[Early pulmonary changes caused by amiodarone].
Aktuelle Radiol. 1996 Sep;6(5):235-8.

引用本文的文献

1
Amiodarone-induced pulmonary interstitial fibrosis.胺碘酮所致的肺间质纤维化。
Intensive Care Med. 2000 Oct;26(10):1585. doi: 10.1007/s001340000657.