Larson Austin, Stidham Timothy, Banerji Shireen, Kaufman Jon
Department of Pediatrics, University of Colorado Anschutz Medical Center, Children's Hospital Colorado, Aurora, USA.
Pediatr Emerg Care. 2013 Mar;29(3):377-9. doi: 10.1097/PEC.0b013e3182854790.
Topical anesthetics are commonly used in many health care settings and for many clinical conditions. However, there are a number of potential adverse effects associated with their use. Their widespread administration can convey a false sense of security and failure to appreciate possible complications. We present the case of an infant with extensive vascular malformations treated with EMLA cream who developed seizures and methemoglobinemia from lidocaine and prilocaine toxicity. We describe the pathophysiology of these morbidities, the use of pulse oximetry in this setting, and the clinical presentation and treatment of methemoglobinemia.
局部麻醉剂在许多医疗环境中常用于多种临床情况。然而，其使用存在一些潜在的不良反应。它们的广泛应用可能会传递一种虚假的安全感，且人们可能未意识到可能的并发症。我们报告一例患有广泛血管畸形的婴儿，使用复方利多卡因乳膏治疗后因利多卡因和丙胺卡因中毒出现癫痫发作和高铁血红蛋白血症。我们描述了这些病症的病理生理学、在此情况下脉搏血氧饱和度测定的应用，以及高铁血红蛋白血症的临床表现和治疗。
