Rosell Arnold E, Botet Mussons F, Figueras Aloy J, Vilanova Juanola J M, Jiménez González R
Servicio de Neonatología, Hospital Clínico y Provincial de Barcelona.
An Esp Pediatr. 1990 Mar;32(3):197-201.
Modern neonatal intensive care has led to a rise in the survival rate of very low birthweight infants (VLBW), but at the same time is a greater number of neurosensorial sequelae. In this study, 50 VLBW (weight less than 1,500 g) babies followed up for at least 12 months are analysed. 18% showed major sequelae (40% of those weighing less than 1,000 g, 12.5% of those weighing 1,000 g or more). The prognostic factors which were most important in the prediction of sequelae were: low birthweight, major irregularities in the EEG, the presence of sepsis, and prolonged ventilotherapy or antibiotherapy.
现代新生儿重症监护使得极低出生体重儿（VLBW）的存活率有所提高，但与此同时，神经感觉后遗症的数量也更多了。在本研究中，对50名随访至少12个月的极低出生体重儿（体重低于1500克）进行了分析。18%的患儿出现了严重后遗症（体重低于1000克的患儿中有40%，体重1000克及以上的患儿中有12.5%）。在预测后遗症方面最重要的预后因素有：低出生体重、脑电图严重异常、败血症的存在以及长时间的通气治疗或抗生素治疗。
