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体重不足1000克婴儿的护理费用。

The cost of care of the less-than-1000-gram infant.

作者信息

Hernandez J A, Offutt J, Butterfield L J

出版信息

Clin Perinatol. 1986 Jun;13(2):461-76.

PMID:3087676
Abstract

One of the most difficult ethical issues in neonatal intensive care concerns the treatment of extremely low birth weight infants (ELBW). Because of their extreme prematurity, aggressive medical intervention is needed to sustain life. Advances in perinatal medicine have made it possible for these extremely immature infants to survive. More importantly, although the mortality and long-term morbidity are high, particularly for infants less than 700 gm, many of the survivors are expected to become productive members of society and produce measurable economic benefit. The limits set for aggressive management of the VLBW infant have gradually been lowered in virtue of the successful survival at each birth weight. It appears that, with each reduction in the birth weight at which maximal efforts should be used, enough babies have survived to encourage us to continue. As we drive to bring the limit of viability to lower gestations and lower birth weights, we are finding some biologic limitations to extrauterine survival that present technology and knowledge cannot overcome. Unquestionably, there is a need for more comprehensive statistics to allow us to define the lower limit of survival. Because of the poor survival rate among infants weighing less than 700 gm, and because of the high cost of their care and statistically poor quality of life among many of the surviving infants, it has been suggested that perhaps a less aggressive approach should be adopted for those extremely immature infants. However, some recent data indicate that aggressive treatment is effective in saving lives, even at the lower spectrum of birth weight, and many of the survivors are normal or have mild handicaps. The importance of economic considerations to solve the ethical dilemma posed by the intensive care of ELBW infants is being questioned. Concerns that reflect moral absolutes cannot be adequately answered in terms of mere dollars and cents. Although the cost of neonatal intensive care is high on a per diem or per case basis, it appears to be reasonable in relation to the health benefits it provides. For infants in the weight class less than 750 gm, probably none would have survived in the absence of neonatal intensive care. We believe that a policy of benign neglect for the ELBW infant is not justified in the present era of perinatal medicine. Given these considerations, we think that aggressive treatment is reasonable, at least initially at birth.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

新生儿重症监护中最棘手的伦理问题之一涉及极低出生体重儿(ELBW)的治疗。由于他们极度早产,需要积极的医疗干预来维持生命。围产期医学的进步使这些极度不成熟的婴儿得以存活。更重要的是,尽管死亡率和长期发病率很高,尤其是对于体重不足700克的婴儿,但许多幸存者有望成为对社会有贡献的成员并产生可衡量的经济效益。鉴于每个出生体重的婴儿都成功存活,对超低出生体重儿积极治疗的界限已逐渐降低。似乎,随着应竭尽全力救治的出生体重下限的每次降低,都有足够数量的婴儿存活下来,鼓励我们继续下去。当我们努力将存活极限降低到更低孕周和更低出生体重时,我们发现宫外存活存在一些生物学限制,现有技术和知识无法克服。毫无疑问,需要更全面的统计数据来帮助我们确定存活下限。由于体重不足700克的婴儿存活率低,且护理成本高,许多存活婴儿的生活质量在统计学上也较差,有人建议对于那些极度不成熟的婴儿或许应采取不那么积极的治疗方法。然而,一些最新数据表明,积极治疗即使在较低出生体重范围内也能有效挽救生命,而且许多幸存者正常或仅有轻微残疾。经济因素对解决ELBW婴儿重症监护所带来的伦理困境的重要性正受到质疑。仅从金钱角度无法充分回答那些反映道德绝对准则的担忧。尽管新生儿重症监护的每日费用或每个病例的费用很高,但相对于其提供的健康益处而言似乎是合理的。对于体重不足750克的婴儿,如果没有新生儿重症监护,可能无一能够存活。我们认为,在当前围产期医学时代,对ELBW婴儿采取放任不管的政策是不合理的。考虑到这些因素,我们认为积极治疗是合理的,至少在出生时最初阶段是如此。(摘要截选至400字)

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