莳萝（莳萝）提取物可提高大鼠交配频率和睾丸酪氨酸蛋白磷酸化水平。
Anethum graveolens Linn. (dill) extract enhances the mounting frequency and level of testicular tyrosine protein phosphorylation in rats.
机构信息
Department of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
出版信息
J Zhejiang Univ Sci B. 2013 Mar;14(3):247-52. doi: 10.1631/jzus.B1200287.
OBJECTIVE
To investigate the effect of Anethum graveolens (AG) extracts on the mounting frequency, histology of testis and epididymis, and sperm physiology.
METHODS
Male rats induced by cold immobilization before treating with vehicle or AG extracts [50, 150, and 450 mg/kg body weight (BW)] via gastric tube for consecutive 1, 7, and 14 d were examined for mounting frequency, testicular phosphorylation level by immunoblotting, sperm concentration, sperm acrosome reaction, and histological structures of testis and epididymis, respectively.
RESULTS
AG (50 mg/kg BW) significantly increased the mounting frequency on Days 1 and 7 compared to the control group. Additionally, rat testis treated with 50 mg/kg BW AG showed high levels of phosphorylated proteins as compared with the control group. In histological analyses, AG extract did not affect the sperm concentration, acrosome reaction, and histological structures of testis and epididymis.
CONCLUSIONS
AG extract enhances the aphrodisiac activity and is not harmful to sperm and male reproductive organs.
目的
研究茴芹提取物对交配频率、睾丸和附睾组织学以及精子生理学的影响。
方法
通过灌胃给予雄性大鼠 vehicle 或茴芹提取物（50、150 和 450mg/kg 体重），连续 1、7 和 14 天，在冷束缚诱导前处理雄性大鼠，然后检测交配频率、免疫印迹法检测睾丸磷酸化水平、精子浓度、精子顶体反应以及睾丸和附睾的组织学结构。
结果
与对照组相比，AG（50mg/kg BW）在第 1 天和第 7 天显著增加了交配频率。此外，与对照组相比，用 50mg/kg BW AG 处理的大鼠睾丸显示出高水平的磷酸化蛋白。在组织学分析中，AG 提取物对精子浓度、顶体反应以及睾丸和附睾的组织学结构没有影响。
结论
茴芹提取物增强了壮阳作用，且对精子和男性生殖器官没有危害。
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