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头颈部浅表基底细胞癌。

Superficial basal cell carcinomas of the head and neck.

机构信息

Department of Dermatology, Emory University, Atlanta, Georgia, USA.

出版信息

Dermatol Surg. 2013 Jul;39(7):1003-8. doi: 10.1111/dsu.12178. Epub 2013 Mar 6.

Abstract

BACKGROUND

Superficial basal cell carcinomas (BCC) are often considered a non-aggressive form of skin cancer, most often found on the trunk in younger patients.

OBJECTIVE

To determine the characteristics of superficial BCC of the head and neck.

MATERIALS AND METHODS

A retrospective review of patients undergoing Mohs micrographic surgery (MMS) for the treatment of a purely superficial BCC on the head and neck region was performed.

RESULTS

Superficial BCC occurred more commonly in women (66.5%) than men (33.5%), most often on chronically sun-exposed skin such as the central face and nose. Women developed superficial BCC at a younger age than men (58 vs 63 years old, p = 0.02). The clinical sizes of the tumors were significantly smaller than the final Mohs defects for all locations on the head and neck, excluding ears and scalp. Recurrence rates after MMS were 3.6% despite negative histologic margins at the time of surgery.

CONCLUSION

Superficial BCC are a unique subtype of BCC that tend to occur in younger patients, particularly women. Mohs surgeons need to be familiar with these tumors on the head and neck given their propensity for skip-lesions, higher recurrence rates, and significantly larger defect sizes than would be expected clinically.

摘要

背景

浅表基底细胞癌(BCC)通常被认为是一种非侵袭性皮肤癌,多见于年轻患者的躯干。

目的

确定头颈部浅表 BCC 的特征。

材料与方法

对接受Mohs 显微外科手术(MMS)治疗头颈部单纯浅表 BCC 的患者进行回顾性研究。

结果

女性(66.5%)比男性(33.5%)更常发生浅表 BCC,最常见于慢性暴露于阳光的部位,如面部中央和鼻子。女性比男性更早发生浅表 BCC(58 岁比 63 岁,p=0.02)。除耳部和头皮外,头颈部所有部位的肿瘤临床大小均明显小于最终 Mohs 缺损。MMS 后的复发率为 3.6%,尽管手术时组织学边缘为阴性。

结论

浅表 BCC 是 BCC 的一种独特亚型,倾向于发生在年轻患者,尤其是女性中。由于存在跳跃性病变、更高的复发率以及与临床预期相比显著更大的缺损大小,Mohs 外科医生需要熟悉这些头颈部的肿瘤。

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