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MRI 与磁共振波谱分析显示两例免疫功能低下患者由枝顶孢霉引起的多发性脑脓肿。

MRI with Magnetic Resonance Spectroscopy of multiple brain abscesses secondary to Scedosporium apiospermum in two immunocompromised patients.

机构信息

The Ohio State University, Department of Radiology, Columbus, OH 43210, USA.

出版信息

Clin Imaging. 2013 Mar-Apr;37(2):361-6. doi: 10.1016/j.clinimag.2012.04.016. Epub 2012 Jun 8.

DOI:10.1016/j.clinimag.2012.04.016
PMID:23465993
Abstract

Scedosporium apiospermum is a deadly fungal infection that can infect the central nervous system, particularly in immunocompromised patients. We present two cases of Scedosporium brain abscesses. The first case was fatal and relevant conventional MRI and MR spectroscopy findings are discussed. To our knowledge, this is the first reported case of MR spectroscopy in Scedosporium apiospermum abscesses. In the second case, the patient recovered and conventional MR findings are followed over several months. In the appropriate clinical setting, conventional MR imaging and MR spectroscopy may facilitate diagnosis, earlier initiation of antifungal pharmacotherapy and surgical intervention in this frequently fatal infection.

摘要

枝顶孢属是一种致命的真菌感染,可感染中枢神经系统,尤其是免疫功能低下的患者。我们报告了两例枝顶孢属脑脓肿。第一例是致命的,讨论了相关的常规 MRI 和 MR 光谱学发现。据我们所知,这是首例枝顶孢属脓肿的 MR 光谱学报告。在第二例中,患者康复,常规 MR 检查结果在几个月内进行了随访。在适当的临床环境下,常规磁共振成像和磁共振波谱学可能有助于诊断,更早地开始抗真菌药物治疗和手术干预,这是一种经常致命的感染。

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