Traoré B, Keita M, Diane S, Dankoro A, Kabba I S, Keita N
Unit of Surgical Oncologyof Donka, POBOX: 5575 Conakry, Guinea.
West Afr J Med. 2012 Oct-Dec;31(4):227-31.
The aim of this study was to describe the characteristics and trends in the number of patients presenting with breast diseases (BD), their evolution in time, and the referral route.
We reviewed all patients with breast disease who consulted at the Unit of Surgical Oncology of Donka from May 2007 to December 2009, examining the distribution of breast diseases. The numbers of women diagnosed with breast cancers was analysed with respect to time and referral source.
There was a progressive increase in the number of patients presenting with breast diseases from year to year: 66 cases in 2007, 134 in 2008 and 227 in 2009. Of 423 patients with breast disease, 184 (43.5%) were diagnosed with breast cancer: 178 women and 6 men. Moreover, the percentage with breast cancer varied significantly according to referral route (p<10-3); 56.0% among patients referred by health professionals and 22.3% in women who self-referred. Mean age at diagnosis of breast cancer was 48 years (n=178), 52.2% were post-menopausal. Women with breast cancer had on average 4.7 full term pregnancies. The tumor was considered aggressive in 62.9% of women because of the rapidity of its evolution. Early stage at diagnosis was made only for 4.3% of the cases. The hormone receptor were positive in 4 of 13 cases (30.7%), and the Cerb2 oncogene was over expressed in 8 of 11 cases (72.7%).
A better organisation of the consultation services in a unit of oncology in a developing country can allow a better sorting and a good orientation of the patients and thus allow the early detection of the breast cancer. This requires adequate awareness of the population, a better involvement and adequate training of the health professionals dedicated to the tasks. The study of the Cerb2's expression and the hormone receptor are to be considered for better understanding the aggressiveness of the breast cancer found in our practice.
本研究旨在描述乳腺疾病（BD）患者的特征、数量趋势、随时间的演变情况以及转诊途径。
我们回顾了2007年5月至2009年12月在东卡外科肿瘤科室就诊的所有乳腺疾病患者，分析乳腺疾病的分布情况。对确诊为乳腺癌的女性患者数量按时间和转诊来源进行了分析。
每年乳腺疾病患者数量呈逐年递增趋势：2007年66例，2008年134例，2009年227例。在423例乳腺疾病患者中，184例（43.5%）被诊断为乳腺癌：178名女性和6名男性。此外，乳腺癌的比例因转诊途径不同而有显著差异（p<10-3）；由医疗专业人员转诊的患者中为56.0%，自行转诊的女性中为22.3%。乳腺癌确诊时的平均年龄为48岁（n=178），52.2%为绝经后女性。患有乳腺癌的女性平均有4.7次足月妊娠。由于肿瘤发展迅速，62.9%的女性被认为肿瘤具有侵袭性。仅4.3%的病例在诊断时处于早期阶段。13例中有4例（30.7%）激素受体呈阳性，11例中有8例（72.7%）Cerb2癌基因过度表达。
在发展中国家的肿瘤科室更好地组织会诊服务，可以使患者得到更好地分类和引导，从而实现乳腺癌的早期发现。这需要民众有足够的认识，致力于此项工作的医疗专业人员有更好的参与度和充分的培训。为了更好地了解我们在实践中发现的乳腺癌的侵袭性，应考虑研究Cerb2的表达和激素受体情况。
