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To cool or not to cool non-shockable cardiac arrest patients: it is time for randomized controlled trials.

作者信息

Deye Nicolas, Arrich Jasmin, Cariou Alain

出版信息

Intensive Care Med. 2013 May;39(5):966-9. doi: 10.1007/s00134-013-2877-0. Epub 2013 Mar 7.

DOI:10.1007/s00134-013-2877-0
PMID:23468048
Abstract
摘要

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To cool or not to cool non-shockable cardiac arrest patients: it is time for randomized controlled trials.
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A review of the utility of a hypothermia protocol in cardiac arrests due to non-shockable rhythms.低温治疗方案在非可电击心律导致的心脏骤停中的效用综述。
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Treatment and outcomes of ST segment elevation myocardial infarction and out-of-hospital cardiac arrest in a regionalized system of care based on presence or absence of initial shockable cardiac arrest rhythm.基于初始可电击性心脏骤停节律的有无,在区域化医疗体系中 ST 段抬高型心肌梗死和院外心脏骤停的治疗和结局。
Am J Cardiol. 2014 Oct 1;114(7):968-71. doi: 10.1016/j.amjcard.2014.07.006. Epub 2014 Jul 16.
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March 2014 Annals of Emergency Medicine Journal Club. Is it still cool to cool? Interpreting the latest hypothermia for cardiac arrest trial.
Ann Emerg Med. 2014 Mar;63(3):368-9. doi: 10.1016/j.annemergmed.2014.01.001.
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Therapeutic hypothermia after out-of-hospital cardiac arrest in Finnish intensive care units: the FINNRESUSCI study.芬兰重症监护病房院外心脏骤停后治疗性低温:FINNRESUSCI 研究。
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Annals of Emergency Medicine Journal Club. Is it still cool to cool? Interpreting the latest hypothermia for cardiac arrest trial: answers to the March 2014 Journal Club questions.《急诊医学年鉴》期刊俱乐部。低温治疗还“潮”吗?解读最新的心脏骤停低温治疗试验:2014年3月期刊俱乐部问题解答
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Caution when defining prolonged downtime in out of hospital cardiac arrest as extracorporeal cardiopulmonary resuscitation becomes accessible and feasible.当院外心脏骤停中长时间停机的定义因体外心肺复苏变得可行而受到关注时。
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引用本文的文献

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Breakthrough in cardiac arrest: reports from the 4th Paris International Conference.心脏骤停的突破:第四届巴黎国际会议报告。
Ann Intensive Care. 2015 Dec;5(1):22. doi: 10.1186/s13613-015-0064-x. Epub 2015 Sep 17.
2
Therapeutic hypothermia after nonshockable cardiac arrest: the HYPERION multicenter, randomized, controlled, assessor-blinded, superiority trial.非可电击心律心脏骤停后的治疗性低温:HYPERION多中心、随机、对照、评估者盲法、优效性试验
Scand J Trauma Resusc Emerg Med. 2015 Mar 7;23:26. doi: 10.1186/s13049-015-0103-5.
3
Comment on Debaty et al.: impact of intra-arrest therapeutic hypothermia in outcomes of prehospital cardiac arrest: a randomized controlled trial.

本文引用的文献

1
Therapeutic hypothermia after out-of-hospital cardiac arrest in Finnish intensive care units: the FINNRESUSCI study.芬兰重症监护病房院外心脏骤停后治疗性低温:FINNRESUSCI 研究。
Intensive Care Med. 2013 May;39(5):826-37. doi: 10.1007/s00134-013-2868-1. Epub 2013 Feb 16.
2
Hypothermia for neuroprotection in adults after cardiopulmonary resuscitation.心肺复苏后成人低温神经保护治疗
Cochrane Database Syst Rev. 2012 Sep 12(9):CD004128. doi: 10.1002/14651858.CD004128.pub3.
3
Safety profile and outcome of mild therapeutic hypothermia in patients following cardiac arrest: systematic review and meta-analysis.
对德巴蒂等人的评论:院内心脏骤停治疗性低温对院外心脏骤停结局的影响:一项随机对照试验
Intensive Care Med. 2015 Jan;41(1):171. doi: 10.1007/s00134-014-3556-5. Epub 2014 Nov 19.
4
Hypothermia after cardiac arrest as a novel approach to increase survival in cardiopulmonary cerebral resuscitation: a review.心脏骤停后低温作为提高心肺脑复苏生存率的新方法:综述
Iran Red Crescent Med J. 2014 Jul;16(7):e17497. doi: 10.5812/ircmj.17497. Epub 2014 Jul 5.
5
Characteristics and prognosis of sudden cardiac death in Greater Paris: population-based approach from the Paris Sudden Death Expertise Center (Paris-SDEC).大巴黎地区心源性猝死的特征和预后:来自巴黎猝死专家中心(Paris-SDEC)的基于人群的研究。
Intensive Care Med. 2014 Jun;40(6):846-54. doi: 10.1007/s00134-014-3252-5. Epub 2014 Mar 22.
心脏骤停后患者接受轻度治疗性低温治疗的安全性和结局:系统评价和荟萃分析。
Emerg Med J. 2013 Feb;30(2):91-100. doi: 10.1136/emermed-2012-201120. Epub 2012 Jun 3.
4
Hypothermia for neonatal hypoxic ischemic encephalopathy: an updated systematic review and meta-analysis.新生儿缺氧缺血性脑病的低温治疗:一项更新的系统评价和荟萃分析。
Arch Pediatr Adolesc Med. 2012 Jun 1;166(6):558-66. doi: 10.1001/archpediatrics.2011.1772.
5
The beneficial effect of mild therapeutic hypothermia depends on the time of complete circulatory standstill in patients with cardiac arrest.轻度治疗性低温的有益效果取决于心脏骤停患者完全循环停止的时间。
Resuscitation. 2012 May;83(5):596-601. doi: 10.1016/j.resuscitation.2011.11.019. Epub 2011 Nov 29.
6
Therapeutic hypothermia is associated with improved neurologic outcome and survival in cardiac arrest survivors of non-shockable rhythms.治疗性低温与非颤动感心律失常心脏骤停幸存者的神经功能结局和存活率改善相关。
Resuscitation. 2012 Feb;83(2):202-7. doi: 10.1016/j.resuscitation.2011.08.005. Epub 2011 Aug 22.
7
Does therapeutic hypothermia benefit adult cardiac arrest patients presenting with non-shockable initial rhythms?: A systematic review and meta-analysis of randomized and non-randomized studies.治疗性低温对初始非可电击节律的成年心脏骤停患者是否有益?:随机和非随机研究的系统评价和荟萃分析。
Resuscitation. 2012 Feb;83(2):188-96. doi: 10.1016/j.resuscitation.2011.07.031. Epub 2011 Aug 9.
8
Early-onset pneumonia after cardiac arrest: characteristics, risk factors and influence on prognosis.心搏骤停后早发性肺炎:特征、危险因素及其对预后的影响。
Am J Respir Crit Care Med. 2011 Nov 1;184(9):1048-54. doi: 10.1164/rccm.201102-0331OC.
9
Mild therapeutic hypothermia is associated with favourable outcome in patients after cardiac arrest with non-shockable rhythms.轻度治疗性低温与心搏骤停伴非可电击节律患者的有利转归相关。
Resuscitation. 2011 Sep;82(9):1162-7. doi: 10.1016/j.resuscitation.2011.05.022. Epub 2011 Jun 12.
10
Impact of therapeutic hypothermia onset and duration on survival, neurologic function, and neurodegeneration after cardiac arrest.心脏骤停后治疗性低温的开始时间和持续时间对生存率、神经功能和神经退行性变的影响。
Crit Care Med. 2011 Jun;39(6):1423-30. doi: 10.1097/CCM.0b013e318212020a.