Huhn R G, Baldwin C D, Cardella M A
Am J Vet Res. 1975 Jan;36(1):71-4.
Resistance to clinical and renal leptospirosis in dogs vaccinated with a bacterin containing Leptospira interrogans serotype canicola and Leptospira interrogans serotype icterohaemorrhagiae was demonstrated. The relationship between resistance induced in vaccinated dogs and that induced in vaccinated hamsters was also demonstrated, using criteria of leptospiremia, renal infection, leptospiruria, and clinical signs of disease in dogs and death in hamsters.
已证明，用含有犬型问号钩端螺旋体和出血性黄疸型问号钩端螺旋体的菌苗接种的犬，对临床型和肾型钩端螺旋体病具有抵抗力。利用犬的钩端螺旋体血症、肾脏感染、钩端螺旋体尿以及疾病的临床症状和仓鼠死亡情况等标准，还证明了接种疫苗的犬所诱导的抵抗力与接种疫苗的仓鼠所诱导的抵抗力之间的关系。
