Hofhuis W J, Oranje A P, Bouquet J, Sinaasappel M
Department of Paediatrics, Erasmus University, Rotterdam, The Netherlands.
Eur J Pediatr. 1990 May;149(8):526-8. doi: 10.1007/BF01957684.
Blue rubber-bleb naevus (BRBN) syndrome is a rare disorder characterized by subcutaneous and gastrointestinal haemangiomas. The latter may lead to bleeding complications. A case is reported in which a process of chronic intravascular coagulation resulted in serious thrombotic complications. In the presence of a chronic consumption coagulopathy, it remains uncertain whether antiplatelet drugs are of prophylactic antithrombotic value.
蓝色橡皮疱痣（BRBN）综合征是一种罕见的疾病，其特征为皮下和胃肠道血管瘤。后者可能导致出血并发症。本文报道了一例慢性血管内凝血过程导致严重血栓形成并发症的病例。在存在慢性消耗性凝血病的情况下，抗血小板药物是否具有预防性抗血栓形成价值仍不确定。
