Hoekstra H J, Mehta D M, Oosterhuis J W, Westra P, van den Dungen J, Dijkstra R G
Division of Surgical Oncology, Gronigen University Hospital, The Netherlands.
Eur J Surg Oncol. 1990 Jun;16(3):240-7.
Intra-operative electron beam radiotherapy is a new treatment modality. The abdomen is the area of greatest potential applicability of IORT and therefore its effect on retroperitoneal structures was investigated in a canine model. The retroperitoneal structures tolerate 30 to 40 Gy well, with the exception of the radiation-sensitive ureter which showed fibrosis. Twenty to 25 Gy is within the safe dose limits for the clinical application of IORT.
术中电子束放射治疗是一种新的治疗方式。腹部是术中放射治疗（IORT）最具潜在应用价值的区域，因此在犬模型中研究了其对腹膜后结构的影响。腹膜后结构对30至40戈瑞的剂量耐受性良好，但对辐射敏感的输尿管出现了纤维化。20至25戈瑞在IORT临床应用的安全剂量范围内。
