Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, Ban Ciao, New Taipei City, Taiwan.
Int J Infect Dis. 2013 Aug;17(8):e634-7. doi: 10.1016/j.ijid.2013.01.016. Epub 2013 Mar 6.
This nationwide study aimed to estimate the risk of pneumonia during a 90-day period following diagnosis with pyogenic liver abscess (PLA) compared to individuals who did not suffer PLA.
We investigated the incidence of pneumonia during the 90 days after diagnosis of PLA among 12 868 patients who received medical services for this condition, and compared it to that of 64 340 controls who received medical services for other medical conditions.
We found that the incidence rates of pneumonia were 9.59 and 1.87 per 10 000 person-days in patients with and without PLA, respectively. Stratified Cox proportional hazard regressions found that the hazard ratio for pneumonia among patients with PLA was 5.28 times higher than that of patients without PLA after adjusting for potential confounding factors. We further found Klebsiella pneumoniae to be the causative organism in 84.9% of the cases, but in only 11.7% of the comparison group.
Our study suggests an increased risk of pneumonia among individuals who have suffered a PLA.
本全国性研究旨在评估化脓性肝脓肿（PLA）诊断后 90 天内肺炎的发病风险，与未患 PLA 的个体进行比较。
我们调查了 12868 名接受 PLA 治疗的患者在 PLA 诊断后 90 天内肺炎的发病率，并与接受其他医疗条件治疗的 64340 名对照者进行了比较。
我们发现，患有和未患有 PLA 的患者肺炎的发病率分别为每 10000 人日 9.59 和 1.87。分层 Cox 比例风险回归发现，在调整潜在混杂因素后，PLA 患者肺炎的危险比是非 PLA 患者的 5.28 倍。我们进一步发现，肺炎克雷伯菌在 84.9%的病例中为致病病原体，但在对照组中仅占 11.7%。
我们的研究表明，患有 PLA 的个体肺炎发病风险增加。
