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颈动脉内膜切除术——在神经外科医生手中安全有效:一位外科医生25年的经验

Carotid endarterectomy—safe and effective in a neurosurgeon's hands: a 25-year single-surgeon experience.

作者信息

Mukerji Nitin, Manjunath Prasad Kuskoor Seetharam, Vivar Ramon, Mendelow Alexander David

机构信息

The James Cook University Hospital, Middlesbrough, United Kingdom.

The Neurosurgery Clinic, Guatemala City, Guatemala.

出版信息

World Neurosurg. 2015 Jan;83(1):74-9. doi: 10.1016/j.wneu.2013.02.088. Epub 2013 Mar 5.

Abstract

OBJECTIVE

Carotid endarterectomy (CEA) is a procedure performed by both vascular surgeons and neurosurgeons in the UK. We present a single neurosurgeon's experience of 728 CEAs over 25 years, performed under both general and local anesthesia, and discuss the results in this context. Our objective was to report on the efficacy of CEA in the hands of a neurosurgeon.

METHODS

Prospective outcome data were collected for all patients who underwent CEA performed by the senior author (A.D.M.) from 1987 to 2011. Data evaluated included patient age, sex, surgical indication, preoperative characteristics, diagnostic modalities used, shunt usage, operative time, any neurological deterioration during or after surgery, and early postoperative problems. Outcome measures used were 30-day death and 30-day disabling stroke. The results were tabulated and analyzed using JMP 8.0.2 (SAS Inc., Cary, NC).

RESULTS

The 30-day death rate was 0.8% and the 30-day disabling stroke rate was 1.7% in our series. The mean operative time was 135 minutes (±38.1), and the mean clamp time was 28.4 minutes (±8.5). In the subset of patients who had the operation performed under local anesthesia (n = 616), the disabling stroke rate was 1.6% and the death rate was 0.6%. In the subset of asymptomatic patients (n = 194), the 30-day death and 30-day disabling stroke rates were each 1%. Postoperative complications were uncommon.

CONCLUSIONS

According to our data, CEA under local anesthesia is safe procedure in the hands of a neurosurgeon and would be recommended according to the clinical presentation and local guidelines.

摘要

目的

在英国,颈动脉内膜切除术(CEA)可由血管外科医生和神经外科医生进行。我们介绍了一位神经外科医生在25年里进行728例CEA手术的经验,这些手术在全身麻醉和局部麻醉下完成,并在此背景下讨论结果。我们的目的是报告神经外科医生实施CEA的疗效。

方法

收集了1987年至2011年由资深作者(A.D.M.)实施CEA手术的所有患者的前瞻性结果数据。评估的数据包括患者年龄、性别、手术指征、术前特征、使用的诊断方法、分流管使用情况、手术时间、手术期间或术后任何神经功能恶化情况以及术后早期问题。使用的结果指标是30天死亡率和30天致残性卒中发生率。结果进行列表并使用JMP 8.0.2(SAS公司,北卡罗来纳州卡里)进行分析。

结果

在我们的系列研究中,30天死亡率为0.8%,30天致残性卒中发生率为1.7%。平均手术时间为135分钟(±38.1),平均夹闭时间为28.4分钟(±8.5)。在局部麻醉下进行手术的患者亚组(n = 616)中,致残性卒中发生率为1.6%,死亡率为0.6%。在无症状患者亚组(n = 194)中,30天死亡率和30天致残性卒中发生率均为1%。术后并发症并不常见。

结论

根据我们的数据,神经外科医生实施局部麻醉下的CEA是一种安全的手术,可根据临床表现和当地指南推荐使用。

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