Department of Health Sciences, University of York, Heslington, York, UK.
Drug Alcohol Depend. 2013 Jul 1;131(1-2):1-22. doi: 10.1016/j.drugalcdep.2013.01.023. Epub 2013 Mar 6.
There is growing interest in pro-active detection and provision of interventions for heavy alcohol use in the general hospital inpatient population. We aimed to determine, from the available evidence, the effectiveness of interventions in reducing alcohol consumption among general hospital inpatient heavy alcohol users.
The following databases were searched for completed and on-going randomised and non-randomised controlled studies published up to November 2012: MEDLINE; C2-SPECTR; CINAHL; The Cochrane Library; Conference Proceedings Citation Index: Science; EMBASE; HMIC; PsycInfo; Public Health Interventions Cost Effectiveness Database (PHICED); and ClinicalTrials.gov. Studies were screened independently by two reviewers. Data extraction was performed by one reviewer and independently checked by a second.
Twenty-two studies which met the inclusion criteria enrolled 5307 participants in total. All interventions were non-pharmacological and alcohol focused. Results from single session brief interventions and self-help literature showed no clear benefit on alcohol consumption outcomes, with indications of benefit from some studies but not others. However, results suggest brief interventions of more than one session could be beneficial on reducing alcohol consumption, especially for non-dependent patients. No active intervention was found superior over another on alcohol consumption and other outcomes.
Brief interventions of more than one session could be beneficial on reducing alcohol consumption among hospital inpatients, especially for non-dependent patients. However, additional evidence is still needed before more definitive conclusions can be reached.
越来越多的人对在综合医院住院患者人群中积极主动地发现和提供干预措施以治疗重度酒精使用问题产生了兴趣。我们旨在根据现有证据确定干预措施在减少综合医院住院重度酒精使用者的饮酒量方面的有效性。
截至 2012 年 11 月,我们检索了以下数据库中已完成和正在进行的随机和非随机对照研究:MEDLINE;C2-SPECTR;CINAHL;Cochrane 图书馆;会议论文引文索引:科学;EMBASE;HMIC;PsycInfo;公共卫生干预成本效益数据库(PHICED);以及 ClinicalTrials.gov。两位评审员独立筛选了研究。一位评审员进行数据提取,另一位独立核对。
共有 22 项符合纳入标准的研究共纳入了 5307 名参与者。所有干预措施均为非药物且专注于酒精问题。单次简短干预和自助文献的结果并未显示出对饮酒量结果有明显的益处,一些研究表明有获益,但另一些研究则没有。然而,结果表明,多次简短干预可能有助于减少饮酒量,尤其是对非依赖患者。在饮酒量和其他结局方面,没有发现哪种积极干预措施优于其他措施。
多次简短干预可能有助于减少住院患者的饮酒量,尤其是对非依赖患者。然而,在得出更明确的结论之前,仍需要更多的证据。