胃肠胰神经内分泌肿瘤的预后和预测生物标志物

Prognostic and predictive biomarkers in gastroenteropancreatic neuroendocrine tumors.

作者信息

Stevenson Ryan, Libutti Steven K, Saif Muhammad Wasif

机构信息

Tufts University School of Medicine, Boston, MA, USA.

出版信息

JOP. 2013 Mar 10;14(2):155-7. doi: 10.6092/1590-8577/1472.

DOI:10.6092/1590-8577/1472

PMID:23474561

Abstract

Neuroendocrine tumors (NET) are a diverse group of tumors that derive from epithelial cells with neuroendocrine differentiation. Gastroenteropancreatic NETs are a subset of NET that arise from the gastrointestinal tract. The natural history and prognosis varies widely between different gastroenteropancreatic NETs, highlighting the importance of identifying accurate prognostic and predictive biomarkers. At the 2013 ASCO Gastrointestinal Cancers Symposium, De Braud et al. (Abstract #186) and Bellister et al. (Abstract #163) present data on two new possible biomarkers.

摘要

神经内分泌肿瘤（NET）是一组源自具有神经内分泌分化的上皮细胞的多种肿瘤。胃肠胰神经内分泌肿瘤是NET的一个子集，起源于胃肠道。不同胃肠胰神经内分泌肿瘤的自然病史和预后差异很大，这凸显了识别准确的预后和预测生物标志物的重要性。在2013年美国临床肿瘤学会胃肠道癌症研讨会上，德布劳德等人（摘要#186）和贝利斯特等人（摘要#163）展示了关于两种新的可能生物标志物的数据。