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在肺量计异常筛查中评估 FEV6:意大利药店的首次基于人群的研究。

FEV6 assessment in spirometric abnormalities screening: the first population-based study in Italian pharmacies.

机构信息

Unit of Pneumology, Cardiovascular and Thoracic Department, Citta della Salute e della Scienza di Torino San Giovanni Battista Molinette Hospital, Turin, Italy.

出版信息

Panminerva Med. 2013 Mar;55(1):87-92.

Abstract

AIM

In recent years, the FEV1/FEV in six seconds ratio has been proposed and validated as a parameter for screening of airways obstruction and restriction. In this context an electronic spirometry screening of pharmacy customers could lead to significant benefits such as improving the appropriateness of diagnostic test prescription and facilitating the early diagnosis of asthma and chronic obstructive pulmonary disease (COPD).

METHODS

Customers of 500 pharmacies in the italian Piemonte region were proposed to test their ventilatory function by an electronic spirometer, PiKo-6®, to find out probably obstruction (pO) and probably restriction (pR). All tests have been carried out by purposely trained pharmacists. Moreover, data regarding sampled subjects' gender, age, height, weight, smoke, pharmacology and therapies used were registered. A web application has been created to collect and analyze the data.

RESULTS

Male smokers confirmed a percentage of pO similar to the one predicted in obstructive lung disease (OLD) in international literature (7%); higher percentages of pO (8%) and pR (35%) were instead found in underweight people. When the data are broken down into therapeutic categories, the highest number of pO (12%) and pR (38%) was found in patients in therapy with bronchodilators, in diabetic patients (pR 41%), and in people treated with diuretics (pO 7%, pR 46%)

CONCLUSION

Data seem to suggest the six-second spirometry as a valid screening tool for the detection of possible airway obstruction and restriction in pharmacies setting. Results point out the possibility of rationalizing the access to medical visits and of optimizing prescriptive appropriateness. The above mentioned points will lead to save public money and will strengthen the role of the Community Pharmacy as health posts of Italian Health National System.

摘要

目的

近年来,FEV1/FEV 在六秒内的比值已被提出并验证为筛选气道阻塞和限制的参数。在这种情况下,对药房顾客进行电子肺活量计筛查可能会带来显著的益处,例如提高诊断测试处方的适当性,并促进哮喘和慢性阻塞性肺疾病(COPD)的早期诊断。

方法

意大利皮埃蒙特地区的 500 家药房的顾客被提议通过电子肺活量计 PiKo-6® 测试他们的呼吸功能,以发现可能的阻塞(pO)和可能的限制(pR)。所有测试均由专门培训的药剂师进行。此外,还记录了样本受试者的性别、年龄、身高、体重、吸烟、药理学和使用的疗法等数据。创建了一个网络应用程序来收集和分析数据。

结果

男性吸烟者证实了与国际文献中阻塞性肺病(OLD)预测相似的 pO 百分比(7%);体重不足的人则发现 pO(8%)和 pR(35%)的百分比更高。当将数据细分为治疗类别时,在接受支气管扩张剂治疗的患者(12%的 pO 和 38%的 pR)、糖尿病患者(pR 41%)和接受利尿剂治疗的患者(pO 7%,pR 46%)中发现了最高数量的 pO 和 pR。

结论

数据似乎表明六秒肺活量计是一种有效的筛查工具,可用于检测药房中可能的气道阻塞和限制。结果指出了合理利用医疗访问和优化处方适当性的可能性。上述观点将节省公共资金,并加强社区药房作为意大利国家卫生系统健康哨所的作用。

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