Cagampang F R, Maeda K, Yokoyama A, Ota K
Laboratory of Animal Reproduction, School of Agriculture, Nagoya University, Japan.
Horm Metab Res. 1990 May;22(5):269-72. doi: 10.1055/s-2007-1004900.
The effect of food deprivation on the pulsatile release of LH was examined in the normal cycling and the ovariectomized (OVX) adult female rat. In the cycling animals, there were significant decreases in the mean plasma LH levels as well as the frequency and amplitude of the LH pulse 48 h after the onset of food deprivation. On the other hand, food deprivation for up to 72 h did not cause any changes in pulsatile LH release in the OVX animals. No difference in the changes in body weight and blood glucose concentration were found between the cycling and OVX rats throughout the period of food deprivation for up to 96 h. These findings suggest that ovarian factors play an important role in the early manifestation of the effect of food deprivation on pulsatile LH release and that metabolic changes as expressed by decreases in body weight and blood glucose level per se were not the direct causes in the decrease of LH release during the period of food deprivation.
在正常发情周期和去卵巢（OVX）的成年雌性大鼠中，研究了食物剥夺对促黄体生成素（LH）脉冲式释放的影响。在处于发情周期的动物中，食物剥夺开始48小时后，平均血浆LH水平以及LH脉冲的频率和幅度均显著降低。另一方面，长达72小时的食物剥夺并未导致OVX动物的LH脉冲式释放出现任何变化。在长达96小时的食物剥夺期间，处于发情周期的大鼠和OVX大鼠在体重和血糖浓度变化方面未发现差异。这些发现表明，卵巢因素在食物剥夺对LH脉冲式释放影响的早期表现中起重要作用，并且体重和血糖水平下降所表现出的代谢变化本身并非食物剥夺期间LH释放减少的直接原因。
