Department of Neurosciences and Behavioral Sciences, School of Medicine at Ribeirão Preto, University of São Paulo, São Paulo, Brazil.
Int J Gynaecol Obstet. 2013 May;121(2):123-6. doi: 10.1016/j.ijgo.2012.12.013. Epub 2013 Mar 8.
To determine the effectiveness of a psychological intervention targeting pregnant women with fetal malformation.
A clinical study was conducted that enrolled 65 pregnant women attending Clinics Hospital at Ribeirão Preto, University of São Paulo, Brazil, between February 2004 and May 2008. Participants were allocated to 1 of 4 groups: normal pregnancy (NP), fetal malformation (FM), fetal or neonatal death (FD), and control (CG). Psychological intervention-including support, empathy, education, and desensitization-was provided to the NP, FM, and FD groups. Women in CG did not receive the intervention and were assessed in the postnatal period only. Anxiety was measured using the Hospital Anxiety and Depression (HAD) scale. Depression was measured by HAD and the Edinburgh Postnatal Depression Scale.
Significant reductions from baseline were observed in anxiety and depression scores after psychological intervention in the NP and FM groups. Symptom scores in the postnatal period were also significantly reduced among these groups (P<0.001).
Psychological intervention was effective in relieving symptoms of anxiety and depression experienced by pregnant women with fetal malformation.
评估针对胎儿畸形孕妇的心理干预措施的有效性。
本临床研究纳入了 2004 年 2 月至 2008 年 5 月期间在巴西圣保罗大学里贝朗普雷图临床医院就诊的 65 名孕妇。将参与者分为 4 组：正常妊娠（NP）组、胎儿畸形（FM）组、胎儿或新生儿死亡（FD）组和对照组（CG）。NP、FM 和 FD 组接受了包括支持、共情、教育和脱敏在内的心理干预，CG 组未接受干预，仅在产后进行评估。采用医院焦虑抑郁量表（HAD）评估焦虑，采用 HAD 和爱丁堡产后抑郁量表评估抑郁。
NP 和 FM 组在接受心理干预后，焦虑和抑郁评分均较基线显著降低，且这些组别的产后症状评分也显著降低（P<0.001）。
心理干预可有效缓解胎儿畸形孕妇的焦虑和抑郁症状。
