Department of Surgical Oncology, VU University Medical Centre, Amsterdam, The Netherlands.
Breast. 2013 Jun;22(3):238-43. doi: 10.1016/j.breast.2013.02.002. Epub 2013 Mar 9.
Ultrasound-guided surgery (USS) has recently been proven to result in a significant reduction of tumour-involved surgical margins, for patients with palpable invasive breast cancer. The objective of this economic evaluation alongside a randomised trial was to evaluate the costs and benefits of USS compared to palpation-guided surgery (PGS). The hospital perspective was used. On the cost side of the analysis, resource use related to baseline treatment was taken into account and on the benefit side, resource use related to additional treatments was included. On the cost side, the difference in costs per patient was €193 (95% CI €153-€233) with higher costs in the USS group. On the benefit side, the difference in costs per patient was -€349 (95% CI -€591 to -€103) with higher costs in the PGS group. This resulted in a cost decrease of -€154 (95% CI -€388 to €81) in the USS group compared to the PGS group. Intra-operative use of a US system during BCS reduces the rate of tumour-involved margins and thereby the costs of additional treatments.
超声引导手术（USS）最近被证明可显著降低可触及浸润性乳腺癌患者的肿瘤相关手术切缘阳性率。本项随机试验的经济学评价旨在评估 USS 与触诊引导手术（PGS）相比的成本效益。采用医院视角。在分析的成本方面，考虑了基线治疗相关的资源使用情况，在效益方面，纳入了额外治疗相关的资源使用情况。在成本方面，USS 组的每位患者的成本差异为 193 欧元（95%CI 153-233），成本更高。在效益方面，PGS 组的每位患者的成本差异为 -349 欧元（95%CI -591 至 -103），成本更高。因此，与 PGS 组相比，USS 组的成本降低了 -154 欧元（95%CI -388 至 81）。在保乳术中使用术中超声系统可降低肿瘤累及切缘的发生率，从而降低额外治疗的成本。
