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脊髓损伤患者上尿路结石病的外科治疗。

The surgical management of upper tract stone disease among spinal cord-injured patients.

机构信息

Division of Urology, Department of Surgery, Western University, London, Ontario, Canada.

出版信息

Spinal Cord. 2013 Jun;51(6):457-60. doi: 10.1038/sc.2013.15. Epub 2013 Mar 12.

Abstract

STUDY DESIGN

Retrospective cohort study, using linked, population-based health-care data.

OBJECTIVES

To describe the incidence, management and outcomes of surgically treated kidney stones after spinal cord injury (SCI). To evaluate the impact of a past history of kidney stones on the occurrence of kidney stones.

SETTING

Ontario, Canada.

METHODS

A total of 5121 patients were followed a median of 4 years after an incident SCI (occurring between 2002 and 2011). The primary outcome was surgical intervention for upper tract kidney stones.

RESULTS

In follow-up, 66 patients (1.3%) had 89 episodes of surgically treated kidney stones. Treatments included: ureteroscopic lithotripsy (34%), ureteral stent/percutaneous nephrostomy (30%), shockwave lithotripsy (19%) or percutaneous nephrolithotripsy (17%). Following stone treatment, the 30-day mortality rate was low, and the 30-day admission rate to an intensive care unit was 12%. A history of surgically treated kidney stones before SCI (compared with no such history) was associated with a higher risk of kidney stones after SCI (27 vs 3 per 1000 person-years; adjusted hazard ratio 14.74, 95% confidence interval 5.69-38.22).

CONCLUSION

During intermediate follow-up after SCI, surgically treated upper tract kidney stones occur in 1.3% of patients. Ureteroscopy with lithotripsy is the most common treatment. A history of surgically managed kidney stones before SCI portends a higher risk of stones after SCI.

摘要

研究设计

回顾性队列研究,使用关联的基于人群的医疗保健数据。

目的

描述脊髓损伤(SCI)后接受手术治疗的肾结石的发病率、治疗方法和结局。评估肾结石病史对肾结石发生的影响。

设置

加拿大安大略省。

方法

对 5121 例在 2002 年至 2011 年间发生的 SCI 后中位数随访 4 年的患者进行了研究。主要结局是上尿路肾结石的手术干预。

结果

在随访期间,66 例患者(1.3%)发生了 89 例手术治疗的肾结石。治疗方法包括:输尿管镜碎石术(34%)、输尿管支架/经皮肾造瘘术(30%)、体外冲击波碎石术(19%)或经皮肾镜碎石术(17%)。结石治疗后,30 天死亡率较低,入住重症监护病房的 30 天入院率为 12%。SCI 前有肾结石手术史(与无手术史相比)与 SCI 后肾结石风险增加相关(27 比每 1000 人年 3 例;校正后的危险比 14.74,95%置信区间 5.69-38.22)。

结论

在 SCI 后中期随访期间,1.3%的患者接受了上尿路肾结石的手术治疗。输尿管镜碎石术是最常见的治疗方法。SCI 前有肾结石手术史预示着 SCI 后结石风险更高。

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