El-Fattah A M A, Ramzy E
Department of Otolaryngology, Faculty of Medicine, Mansoura University, Egypt.
J Laryngol Otol. 2013 Apr;127(4):383-91. doi: 10.1017/S0022215113000364. Epub 2013 Mar 12.
This double-blind, controlled, parallel-group study was designed to determine the efficacy of pre-emptive triple analgesia for paediatric post-tonsillectomy pain management.
One hundred and thirty-five children were randomised into two groups: pre-emptive triple analgesia (n = 55) and control (n = 80). Pain was assessed using a visual analogue scale (in hospital) and the Parent's Postoperative Pain Measure (at home), and scores recorded.
Visual analogue scale scores on awakening and for 6 hours post-surgery were significantly better in the study group than the control group (p < 0.05). The Parent's Postoperative Pain Measure scores of control group children were significantly higher within the first 3 post-operative days (p = 0.000), with a greater percentage of children experiencing significant pain and requiring more analgesia.
The proposed multimodal, pre-emptive analgesia protocol for paediatric post-tonsillectomy pain results in less post-operative pain, both in hospital or at home.
本双盲、对照、平行组研究旨在确定预先使用三联镇痛法对小儿扁桃体切除术后疼痛管理的疗效。
135名儿童被随机分为两组：预先使用三联镇痛法组（n = 55）和对照组（n = 80）。使用视觉模拟评分法（在医院）和家长术后疼痛评估量表（在家中）评估疼痛情况，并记录分数。
研究组患儿术后苏醒时及术后6小时的视觉模拟评分显著优于对照组（p < 0.05）。对照组患儿的家长术后疼痛评估量表分数在术后前3天显著更高（p = 0.000），经历显著疼痛并需要更多镇痛的患儿比例更大。
所提议的用于小儿扁桃体切除术后疼痛的多模式预先镇痛方案，在医院或家中均可减少术后疼痛。
