Department of Zoology, University of Oxford, South Parks Road, OX1 3PS, UK.
Gen Comp Endocrinol. 2013 Jul 1;188:16-22. doi: 10.1016/j.ygcen.2013.02.013. Epub 2013 Mar 7.
As the last few decades of work has shown, precise regulation of biosynthesis and release of arthropod hormones is essential to cope with environmental stresses and challenges. In crustaceans and insects, the sesquiterpenoids methyl farnesoate (MF), farnesoic acid (FA) and juvenile hormone (JH) regulate many developmental, physiological, and reproductive processes. In this review, we discuss how comparative genomics has and will impact our views on arthropod endocrinology. We will also highlight the current knowledge of regulation of genes involved in arthropod hormone biosynthesis by microRNAs, and describe the potential insights into arthropod endocrinology, evolution, and adaptation that are likely to come from the study of microRNAs.
正如过去几十年的研究工作所表明的那样，精确调节节肢动物激素的生物合成和释放对于应对环境压力和挑战至关重要。在甲壳动物和昆虫中，倍半萜类化合物甲基法呢酯（MF）、法呢酸（FA）和保幼激素（JH）调节着许多发育、生理和生殖过程。在这篇综述中，我们讨论了比较基因组学如何以及将如何影响我们对节肢动物内分泌学的看法。我们还将重点介绍目前关于 microRNAs 调控参与节肢动物激素生物合成的基因的知识，并描述研究 microRNAs 可能为节肢动物内分泌学、进化和适应带来的潜在见解。
