Aminimoghaddam Soheila, Ebrahimi Atefeh-Sadat, Hashemi Forough
Gynecologist-Oncologist, Assistant Professor of Medicine, Department of gynecology, Firoozgar Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Med J Islam Repub Iran. 2012 Nov;26(4):185-8.
Leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. They produce testosterone leading to hyperandrogenism. We present a 41yr old woman with symptoms of virilization and a mass of right adenex via ultra Sonography, and a rise of total and free serum testosterone. An ovarian source of androgen was suspected and a surgery performed. A diagnosis of leydig-stromal cell tumor was confirmed. Our report is a reminder that although idiopathic hirsutism and other benign androgen excess disorder like Polycystic Ovarian Syndrome (PCOs) are common, ovarian mass should be considered in differential diagnosis.
睾丸间质细胞瘤是一种罕见的卵巢肿瘤,属于性索间质肿瘤。它们会产生睾酮,导致高雄激素血症。我们报告了一名41岁女性,她有男性化症状,经超声检查发现右侧附件有肿块,血清总睾酮和游离睾酮水平升高。怀疑雄激素来源于卵巢,遂进行了手术。确诊为睾丸间质细胞瘤。我们的报告提醒,虽然特发性多毛症和其他良性雄激素过多症如多囊卵巢综合征(PCOS)很常见,但在鉴别诊断时应考虑卵巢肿块。