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正常大小卵巢中的莱迪希细胞瘤导致阴蒂肥大:一例报告。

Leydig tumor in normal sized ovaries causing clitoromegaly: A case report.

作者信息

Chavez Thomas F, Singh Minita, Avadhani Vaidehi, Leonis Regina

机构信息

Morehouse School of Medicine Department of Obstetrics and Gynecology, Grady Memorial Hospital, 80 Jesse Hill Jr Drive SE Atlanta, GA 30303.

Morehouse School of Medicine 720 Westview Dr SW Atlanta, GA 30310.

出版信息

Gynecol Oncol Rep. 2024 Feb 21;52:101345. doi: 10.1016/j.gore.2024.101345. eCollection 2024 Apr.

Abstract

We describe an unusual presentation of a rare Leydig tumor presenting in bilateral ovaries that are otherwise normal in size for postmenopausal women. A 66-year-old woman presented with postmenopausal bleeding and during her work-up acutely developed clitoromegaly. Her diagnostic work-up revealed a 1.8 cm left ovarian complex cyst and extremely elevated testosterone levels. Management included hysterectomy and bilateral salpingo-oophorectomy. Final pathology revealed Leydig tumors in the bilateral ovaries. This case discusses a rare presentation of a rare tumor and highlights the importance of a thorough examination of the female genitalia and investigation for root cause.

摘要

我们描述了一例罕见的间质细胞瘤在双侧卵巢的不寻常表现,而这些卵巢对于绝经后女性来说大小正常。一名66岁女性出现绝经后出血,在检查过程中阴蒂突然肿大。她的诊断检查发现左侧卵巢有一个1.8厘米的复杂囊肿,睾酮水平极度升高。治疗包括子宫切除术和双侧输卵管卵巢切除术。最终病理显示双侧卵巢存在间质细胞瘤。本病例讨论了一种罕见肿瘤的罕见表现,并强调了对女性生殖器进行全面检查和追查病因的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/322d/10907142/73b1bb81e09e/gr1a.jpg

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