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A retrospective study of autologous stem cell mobilization to guide an immediate salvage protocol using plerixafor for patients who mobilize stem cells poorly.

作者信息

Hay Annette Elizabeth, Lawrie Alastair, Robinson Nicolas, Dong Bin, Culligan Dominic J

机构信息

Department of Haematology, NHS Grampian, Scotland; NCIC Clinical Trials Group, Kingston, Canada.

出版信息

J Clin Apher. 2013 Oct;28(5):378-80. doi: 10.1002/jca.21274. Epub 2013 Mar 11.

DOI:10.1002/jca.21274
PMID:23483573
Abstract

The addition of plerixafor to G-CSF decreases the risk of failed stem cell collection, but at considerable extra cost. Using a logistic regression model based on 354 autologous mobilizations, we have identified a local minimum peripheral blood CD34 count at which the probability of a successful collection is 50%. This seems an appropriate CD34 count at which to add immediate salvage plerixafor.

摘要

相似文献

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A retrospective study of autologous stem cell mobilization to guide an immediate salvage protocol using plerixafor for patients who mobilize stem cells poorly.
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2
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引用本文的文献

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Peripheral blood stem cell mobilization in multiple myeloma comparison of two consecutive regimens in a limited resources country.多发性骨髓瘤中外周血干细胞动员：资源有限国家两种连续方案的比较
Bone Marrow Transplant. 2017 Feb;52(2):222-227. doi: 10.1038/bmt.2016.246. Epub 2016 Oct 24.