Use of nitric oxide producer L-arginine during infusion therapy of experimental hemorrhagic shock.
作者信息
Grishina G V, Gerbut K A, Remizova M I, Selivanov E A
机构信息
Department of Blood Substitutes and Components, Russian Research Institute of Hematology and Transfusiology, Federal Medical and Biological Agency, St. Petersburg, Russia.
出版信息
Bull Exp Biol Med. 2013 Jan;154(3):312-5. doi: 10.1007/s10517-013-1939-1.
PMID:23484189
Abstract
Experiments on rats showed that infusion of NO precursor L-arginine before bleeding enhanced their tolerance to hemorrhagic shock. When infused after blood loss as a component of saline solution, L-arginine improved efficiency of infusion therapy for hemorrhagic shock and increased survival rate of the animals.
摘要
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