Pu Yuan-Hua, Zhang De-Lin
State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2012 Dec 30;30(6):480-5, 490.
Toxoplasma gondii is a kind of obligate intracellular parasite and causes serious harm to human health and the development of animal husbandry. Recent years, significant research on its mechanism of host-invading and immunology has been conducted, and considerable research progress has been made, which are important for an indepth knowledge of pathogenesis of Toxoplasma gondii and immune prevention. This paper reviews the invading process of the parasite in the viewpoint of molecular and cell biology, and the effects of different kinds of immunocytes and the immune responses in the organs.
弓形虫是一种专性细胞内寄生虫，对人类健康和畜牧业发展造成严重危害。近年来，对其宿主入侵机制和免疫学进行了大量研究，并取得了相当大的研究进展，这对于深入了解弓形虫的发病机制和免疫预防具有重要意义。本文从分子和细胞生物学的角度综述了该寄生虫的入侵过程，以及不同种类免疫细胞的作用和器官中的免疫反应。
