Nowicki Dariusz, Gajewska Lucyna, Sosada Krystyn Andrzej
Powiatowa Stacja Sanitarno-Epidemiologiczna w Czestochowie.
Przegl Epidemiol. 2012;66(4):667-72.
Obligatory reporting of adverse effects following immunization (AEFI) was introduced in Poland in 1995. In 2006-2010 number of AEFI reported to the District Sanitary-Epidemiological Station in Czestochowa was 70. For the same period in the whole country 4552 cases were reported.
Purpose of the study was to perform epidemiological analysis of cases reported in Czestochowa and to compare the results with the data for the whole country.
For analysis AEFI, data was obtained from the AEFI register held in PSSE in Czestochowa, and the data of National Institute of Public Health-PZH for 2006-2010. The analysis included the number and frequency of AEFI, the type of vaccine involved with the cases, and the character of the reaction.
Most frequently, AEFI reported to the PSSE occured after BCG vaccination--15 cases (21.4% of the total) and after DTP--14 cases (20%). AEFI other than BCG occurred in 55 cases, representing 78.6% of all reported. 37 AEFI (53% of all reported cases) was after vaccines with the pertussis component . In all instances, AEFI against measles, mumps and rubella occurred after the first dose of vaccine. In the analyzed period, it was observed steady increase in the total number of AEFI, which was associated with the increase in the number of infections covered by the vaccinations: Haemophilus influenzae type b, pneumococcal, varicella, human papillomavirus, and rotavirus. Adverse events following immunization reported in 2006-2010 to the PSSE in Czestochowa were mild reactions, which did not result in permanent adverse health complications. Trends for changes in the epidemiology ofAEFI in Czestochowa are similar to those in the the entire country.
The observed increase in the total number of AEFI is associated with an increase in the number of vaccinations performed in Poland.
波兰于1995年开始实行免疫接种后不良反应（AEFI）的强制报告制度。2006 - 2010年期间，向琴斯托霍瓦地区卫生防疫站报告的AEFI病例数为70例。同一时期，全国共报告了4552例。
本研究旨在对琴斯托霍瓦报告的病例进行流行病学分析，并将结果与全国数据进行比较。
为分析AEFI，数据取自琴斯托霍瓦PSSE保存的AEFI登记册以及国家公共卫生研究所 - PZH 2006 - 2010年的数据。分析内容包括AEFI的数量和频率、涉及病例的疫苗类型以及反应特征。
向PSSE报告的AEFI最常发生在卡介苗接种后——15例（占总数的21.4%）和白百破疫苗接种后——14例（20%）。卡介苗以外的AEFI有55例，占所有报告病例的78.6%。37例AEFI（占所有报告病例的53%）发生在含百日咳成分的疫苗接种后。在所有情况下，麻疹、腮腺炎和风疹疫苗的AEFI均发生在第一剂疫苗接种后。在分析期间，观察到AEFI总数稳步增加，这与疫苗接种所涵盖的感染数量增加有关：b型流感嗜血杆菌、肺炎球菌、水痘、人乳头瘤病毒和轮状病毒。2006 - 2010年向琴斯托霍瓦PSSE报告 的免疫接种后不良事件均为轻微反应，未导致永久性不良健康并发症。琴斯托霍瓦AEFI流行病学的变化趋势与全国相似。
观察到的AEFI总数增加与波兰疫苗接种数量的增加有关。
