实时三维经食管超声心动图增加了经导管主动脉瓣植入术的价值。
Real-time three-dimensional transesophageal echocardiography adds value to transcatheter aortic valve implantation.
机构信息
Cardiac Unit of King's Health Partners, Denmark Hill, London, United Kingdom.
出版信息
J Am Soc Echocardiogr. 2013 Apr;26(4):359-69. doi: 10.1016/j.echo.2013.01.014. Epub 2013 Feb 26.
BACKGROUND
Successful transcatheter aortic valve implantation (TAVI) mandates comprehensive, accurate multimodality imaging. Echocardiography is involved at all key stages and, with the advent of real-time three-dimensional (3D) transesophageal echocardiography, is uniquely placed to enable periprocedural monitoring. The investigators describe a comprehensive two-dimensional (2D) and 3D echocardiographic protocol, and the additional benefits of 3D TEE, within a high-volume TAVI program.
METHODS
TAVI was performed with 2D and 3D transesophageal echocardiographic and fluoroscopic guidance in consecutive high-risk patients with symptomatic severe aortic stenosis. The role of TEE, including the additive value of 3D TEE, was examined, and procedural and echocardiographic outcomes were evaluated. A 3D sizing transcatheter heart valve (THV) strategy was used, except as mandated by study protocol.
RESULTS
Procedural success was achieved in 99% of 256 patients (mean age, 82.9 ± 7.1 years, mean logistic European System for Cardiac Operative Risk Evaluation score, 21.6 ± 11.2%; mean aortic valve area, 0.63 ± 0.19 cm(2)), with no procedural deaths. Acceptable 2D and 3D transesophageal echocardiographic images were achieved in all patients. Aortic valve annular dimensions by 2D transthoracic echocardiography, 2D TEE, and 3D TEE were 21.6 ± 1.9 mm, 22.5 ± 2.2 mm (P < .001), and 23.0 ± 2.0 mm (P = .004 vs 2D TEE), respectively. The 2D THV sizing strategy would have changed THV selection in 23% of patients, downsizing in most. Three-dimensional TEE provided superior spatial visualization and anatomic orientation and optimized procedural performance. Postprocedural mild, moderate, and severe paravalvular aortic regurgitation was observed in 24%, 3%, and 0% of patients, respectively, with no or trace transvalvular aortic regurgitation in 95%. A second valve was successfully deployed in five patients, and TEE detected five other periprocedural complications.
CONCLUSIONS
A systematic, comprehensive echocardiographic protocol, incorporating the additional benefits of 3D TEE, has a vital role within a TAVI program and, combined with a 3D THV sizing strategy, contributes to excellent outcomes.
背景
经导管主动脉瓣植入术(TAVI)的成功需要全面、准确的多模态成像。超声心动图在所有关键阶段都有参与,并且随着实时三维(3D)经食管超声心动图的出现,它具有独特的优势,可以进行围手术期监测。研究人员描述了一种在大容量 TAVI 计划中使用的全面的二维(2D)和 3D 超声心动图方案,以及 3D TEE 的额外益处。
方法
对连续的高危、有症状的严重主动脉瓣狭窄患者进行 2D 和 3D 经食管超声心动图和透视引导的 TAVI。研究了 TEE 的作用,包括 3D TEE 的附加价值,并评估了手术和超声心动图的结果。除研究方案要求外,还使用了 3D 经导管心脏瓣膜(THV)的 sizing 策略。
结果
256 例患者中有 99%(平均年龄 82.9±7.1 岁,平均欧洲心脏手术风险评估系统评分 21.6±11.2%,平均主动脉瓣面积 0.63±0.19cm2)手术成功,无手术死亡。所有患者均获得可接受的 2D 和 3D 经食管超声心动图图像。二维经胸超声心动图、二维 TEE 和三维 TEE 的主动脉瓣环直径分别为 21.6±1.9mm、22.5±2.2mm(P<.001)和 23.0±2.0mm(P=.004 与二维 TEE)。二维 THV 大小策略将改变 23%患者的 THV 选择,大部分为缩小。3D TEE 提供了更好的空间可视化和解剖方向,并优化了手术性能。术后有 24%、3%和 0%的患者出现轻度、中度和重度瓣周主动脉反流,95%的患者无或微量瓣周主动脉反流。五名患者成功植入第二枚瓣膜,TEE 检测到五例其他围手术期并发症。
结论
在 TAVI 计划中,系统的、全面的超声心动图方案,结合 3D TEE 的额外益处,具有重要作用,结合 3D THV 大小策略,有助于获得良好的结果。