University Clinical Hospital Center "Dr Dragisa Misovic" , Belgrade , Serbia.
Clin Exp Hypertens. 2013;35(8):637-44. doi: 10.3109/10641963.2013.776573. Epub 2013 Mar 13.
The aim of this study was to investigate the impact of nondipping arterial blood pressure pattern and the metabolic syndrome (MS), as well as their interaction, on left ventricular (LV) structural and function remodeling. The study included 352 never-treated hypertensive patients with and without MS. Nondipping pattern and MS, separately, as well as their interaction, significantly impacted LV structure, LV geometry pattern, systolic, diastolic and global function in hypertensive patients. Abdominal obesity was the only MS criterion which was simultaneously associated with LV hypertrophy, LV diastolic dysfunction and, LV global dysfunction.
本研究旨在探讨非杓型血压模式和代谢综合征（MS）及其相互作用对左心室（LV）结构和功能重构的影响。该研究纳入了 352 例未经治疗的高血压患者，其中包括伴或不伴 MS 的患者。非杓型血压模式和 MS 及其相互作用均显著影响高血压患者的 LV 结构、LV 几何形态、收缩功能、舒张功能和整体功能。腹型肥胖是唯一与 LV 肥厚、LV 舒张功能障碍和 LV 整体功能障碍同时相关的 MS 标准。
