Eren Mine Şencan, Durak Hatice
Dokuz Eylül University School of Medicine, Department of Nuclear Medicine, İzmir, Turkey.
Mol Imaging Radionucl Ther. 2012 Aug;21(2):42-6. doi: 10.4274/Mirt.182. Epub 2012 Aug 1.
We aimed to investigate if increased F-18 Fluoro Deoxyglucose (F-18 FDG) uptake observed in vocal cords (VC) of the patients on Positron Emission Tomography/Computarize Tomography (PET/CT) scans is connected to speaking of the patients or not. If so, we expected to detect an increased metabolic activity in Broca's area. In this study, we have retrospectively searched for a correlation between the activity in the Broca's area and vocal cords of patients who had undergone FDG PET for different indications.
FDG PET/CT scans of 30 patients with (VC [+]) and 30 patients without (VC [-]) bilateral F-18 FDG uptake on their vocal cords were retrospectively evaluated. Brain quantification was carried out on NeuroQ software with 20 iterations using patients' transaxial brain cross sections. On the 20th-23rd-26th-29th cross sections, area/whole brain ratios of the right (R) and left (L) for Broca's area were calculated. VC (+) and VC (-) patients' R and L Broca's areas were compared using Student's t-test.
There was no significant difference between the Broca's areas of VC (+) and VC (-) patients. L Broca's areas of both VC (+) and VC (-) patients were more active than R Broca's areas (p<0.05). There was a negative correlation between VC (+) patients' SUVmax values in the vocal cords and the activity in their R Broca's region.
In our study, we did not find a significant difference between Broca's areas of VC (+) patients and VC (-) patients, so the activity in their vocal cords does not seem to be related to increased metabolic activity in Broca's areas. We have concluded that the vocal cord activity is not related to speaking of the patients. The activity in the vocal cord might be due to inflammation or, as in the eye muscles, may be associated with high metabolism in laryngeal muscles.
None declared.
我们旨在研究在正电子发射断层扫描/计算机断层扫描（PET/CT）中观察到的患者声带（VC）中F-18氟脱氧葡萄糖（F-18 FDG）摄取增加是否与患者的说话有关。如果有关，我们期望在布罗卡区检测到代谢活性增加。在本研究中，我们回顾性地寻找了因不同适应症接受FDG PET检查的患者布罗卡区与声带之间的相关性。
回顾性评估30例声带双侧有F-18 FDG摄取（VC [+]）和30例声带无F-18 FDG摄取（VC [-]）患者的FDG PET/CT扫描。使用患者的经轴位脑横断面在NeuroQ软件上进行20次迭代的脑定量分析。在第20、23、26、29个横断面上，计算布罗卡区右侧（R）和左侧（L）的面积/全脑比值。使用学生t检验比较VC（+）和VC（-）患者的R和L布罗卡区。
VC（+）和VC（-）患者的布罗卡区之间无显著差异。VC（+）和VC（-）患者的L布罗卡区均比R布罗卡区更活跃（p<0.05）。VC（+）患者声带中的SUVmax值与其R布罗卡区的活性之间存在负相关。
在我们的研究中，我们未发现VC（+）患者和VC（-）患者的布罗卡区之间存在显著差异，因此他们声带中的活性似乎与布罗卡区代谢活性增加无关。我们得出结论，声带活性与患者的说话无关。声带中的活性可能是由于炎症，或者如眼肌一样，可能与喉肌的高代谢有关。
未声明。
