Robaye P, Dugas M, Breton F, Grob R, Lesèvre N, Renault B
CNRS-URA 654, LENA, hôpital de la Salpêtrière, Paris, France.
Neurophysiol Clin. 1990 Apr;20(1):13-33. doi: 10.1016/s0987-7053(05)80166-2.
Event-related potentials were recorded in 2 groups (attention deficit hyperactivity disorder--ADHD--and normal controls) of 12 male children aged between 6-8 years during 4 categorization tasks. Each task was performed with a different type of visual stimulus; pictures, words, geometrical figures or digits. The amplitudes and latencies of a fronto-central P250 and a parieto-occipital P350 were examined. The overall amplitude of the fronto-central P250 was larger in the ADHD group. However, the overall latency of the parieto-occipital P350 decreased with age; coincidentally, in the control group, the P350 latency measured in the left hemisphere became shorter with age for the words than for the pictures. This was not the case in the ADHD group. These results are discussed in relation to the level of the orienting reaction and the modes (general or differentiated) of cognitive development.
在4项分类任务期间,对两组(注意力缺陷多动障碍——ADHD——组和正常对照组)12名6至8岁的男性儿童记录了事件相关电位。每项任务使用不同类型的视觉刺激进行;图片、单词、几何图形或数字。检测了额中央P250和顶枕P350的波幅和潜伏期。ADHD组额中央P250的总体波幅更大。然而,顶枕P350的总体潜伏期随年龄增长而缩短;巧合的是,在对照组中,左半球测量的单词P350潜伏期随年龄增长比图片的潜伏期缩短得更多。ADHD组则并非如此。结合定向反应水平和认知发展模式(一般或分化)对这些结果进行了讨论。