Vatankulu Mehmet Akif, Koc Fatih, Gul Enes Elvin, Bacaksiz Ahmet, Sonmez Osman, Demir Kenan, Alihanoglu Yusuf, Ari Hatem, Ayhan Selim, Tokac Mehmet
Faculty of Medicine, Cardiology Department, Bezmialem Vakif University, Istanbul, Turkey.
Echocardiography. 2013 Sep;30(8):936-9. doi: 10.1111/echo.12157. Epub 2013 Mar 12.
We aimed to investigate whether coronary sinus (CS) dilatation develops in patients with mitral stenosis (MS) and to demonstrate its relationship with the global myocardial performance of the right ventricle (RV).
We enrolled 34 patients with MS who underwent echocardiography after exhibiting typical symptoms (31 female; mean age 41 ± 12 years) and 20 age- and sex-matched controls without MS who underwent echocardiography (16 female; mean age 38 ± 13 years). The RV myocardial performance index (MPI) was detected using tissue Doppler echocardiography (TDE), and maximum CS diameter was measured from the posterior atrioventricular groove in the apical four-chamber view during the ventricular systole.
The RV MPI was significantly higher in the MS group compared to the control group (0.60 ± 0.11 vs. 0.41 ± 0.08, P < 0.001). Moreover, the maximum CS dimension was higher in the MS group compared to the control group (8.5 ± 1.1 mm vs. 6.5 ± 1.4 mm, P < 0.001). The maximum CS dilatation was positively correlated with the RV MPI (r = 0.691; P < 0.001).
The RV MPI, which represents both systolic and diastolic functions, is increased in patients with MS and correlates with CS dilatation.
我们旨在研究二尖瓣狭窄（MS）患者是否会出现冠状窦（CS）扩张，并证明其与右心室（RV）整体心肌功能的关系。
我们纳入了34例出现典型症状后接受超声心动图检查的MS患者（31例女性；平均年龄41±12岁）以及20例年龄和性别匹配的无MS且接受超声心动图检查的对照者（16例女性；平均年龄38±13岁）。使用组织多普勒超声心动图（TDE）检测RV心肌性能指数（MPI），并在心室收缩期从心尖四腔视图中的后房室沟测量CS最大直径。
与对照组相比，MS组的RV MPI显著更高（0.60±0.11对0.41±0.08，P<0.001）。此外，与对照组相比，MS组的CS最大尺寸更大（8.5±1.1mm对6.5±1.4mm，P<0.001）。CS最大扩张与RV MPI呈正相关（r=0.691；P<0.001）。
代表收缩和舒张功能的RV MPI在MS患者中升高，且与CS扩张相关。
