Department of Cardiology, Keio University Hospital, Tokyo, Japan.
J Cardiovasc Electrophysiol. 2013 Jul;24(7):781-7. doi: 10.1111/jce.12120. Epub 2013 Mar 14.
The ridge between the left pulmonary veins (PV) and the left atrial appendage composes part of the lateral mitral isthmus (LMI). Following circumferential PV isolation and LMI linear ablation for the treatment of atrial fibrillation (AF), a critical pathway might develop over the ridge leading to a ridge-related reentry (RRR).
Out of 61 patients who underwent circumferential PV isolation appended by LMI ablation, 5 patients developed RRR. The diagnosis of RRR was based on (1) macro-reentrant atrial tachycardia involving the septum, anterior and inferior wall of the left atrium; (2) slow conduction along the ridge; (3) wide-split double potentials in the ventricular aspect of the LMI were identified with the coronary sinus (CS) electrodes. RRR was investigated with electroanatomical mapping and entrainment mapping and catheter ablation was carried out in all patients. The mean cycle length (CL) of RRR was 312 ± 82 milliseconds and the PPIs at the left atrial septum, inferior and anterior wall during RRR were 10 ± 6, 12 ± 8, 9 ± 5 milliseconds longer than the RRR CL. The interval of the double potentials recorded in the CS electrodes crossing the LMI was 164 ± 38 milliseconds during RRR and the PPI on the LMI near the mitral annulus was 57 ± 10 milliseconds longer than the RRR CL. Catheter ablation was performed anatomically by targeting the ridge and successfully terminated RRR.
After circumferential PV isolation and ablation for LMI in patients with AF, RRR can develop by utilizing the surviving myocardial tissue of the ridge as a critical pathway.
左肺静脉(PV)与左心耳之间的嵴构成了外侧二尖瓣峡部(LMI)的一部分。在行环肺静脉隔离和 LMI 线性消融术治疗心房颤动(AF)后,嵴上可能会形成一条关键通路,导致嵴相关折返(RRR)。
在接受环肺静脉隔离加 LMI 消融术的 61 例患者中,有 5 例发生了 RRR。RRR 的诊断基于以下几点:(1)涉及左心房间隔、前壁和下壁的大折返性房性心动过速;(2)嵴上的缓慢传导;(3)冠状窦(CS)电极识别到 LMI 心室面的宽分裂双电位。RRR 采用电生理标测和拖带标测进行研究,并对所有患者进行了导管消融。RRR 的平均周长(CL)为 312±82 毫秒,左心房间隔、下壁和前壁的 PPI 在 RRR 期间比 RRR CL 长 10±6、12±8、9±5 毫秒。RRR 期间,CS 电极记录的双电位的间隔为 164±38 毫秒,二尖瓣环附近 LMI 的 PPI 比 RRR CL 长 57±10 毫秒。RRR 时嵴作为关键通路的存活心肌组织可发生折返,采用解剖学方法针对嵴进行消融治疗,成功终止 RRR。
AF 患者行环肺静脉隔离和 LMI 消融术后,RRR 可通过利用嵴上的残存心肌组织作为关键通路而发生。