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[局部照射后大鼠脑血管内皮细胞的早期减少]

[The early decrease in the endothelial cells of the cerebral vessels of rats after local irradiation].

作者信息

Eĭdus L Kh, Liubimov N V, Levitman M Kh, Plotnikova E D

出版信息

Radiobiologiia. 1990 Mar-Apr;30(2):266-9.

PMID:2349388
Abstract

Possible causes of diminution of endothelial cells of rat brain vessels immediately after local irradiation have been investigated. It has been shown that the diminution occurs during the first 24 h following irradiation, its value (-15%) being independent of radiation dose within a wide range (from 5 to 100 Gy), and the cellularity is not restored during the subsequent two weeks of observation. Interphase death of part of cells distinguished by high radiosensitivity seems to be the most probable reason for the population heterogeneity observed.

摘要

对局部照射后大鼠脑血管内皮细胞立即减少的可能原因进行了研究。结果表明,减少发生在照射后的最初24小时内,其值(-15%)在很宽的剂量范围内(从5到100 Gy)与辐射剂量无关,并且在随后两周的观察期内细胞数量未恢复。部分具有高放射敏感性的细胞在间期死亡似乎是观察到的群体异质性最可能的原因。

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[The early decrease in the endothelial cells of the cerebral vessels of rats after local irradiation].[局部照射后大鼠脑血管内皮细胞的早期减少]
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