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一种用于评估儿童后颅窝肿瘤手术结果的决策分析工具——“利物浦神经外科并发症因果关系评估工具”

A decision analysis tool for the assessment of posterior fossa tumour surgery outcomes in children--the "Liverpool Neurosurgical Complication Causality Assessment Tool".

作者信息

Zakaria Rasheed, Ellenbogen Jonathan, Graham Catherine, Pizer Barry, Mallucci Conor, Kumar Ram

机构信息

Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK.

出版信息

Childs Nerv Syst. 2013 Aug;29(8):1277-83. doi: 10.1007/s00381-013-2065-0. Epub 2013 Mar 14.

Abstract

INTRODUCTION

Complications may occur following posterior fossa tumour surgery in children. Such complications are subjectively and inconsistently reported even though they may have significant long-term behavioural and cognitive consequences for the child. This makes comparison of surgeons, programmes and treatments problematic.

MATERIALS AND METHODS

We have devised a causality tool for assessing if an adverse event after surgery can be classified as a surgical complication using a series of simple questions, based on a tool used in assessing adverse drug reactions. This tool, which we have called the "Liverpool Neurosurgical Complication Causality Assessment Tool", was developed by reviewing a series of ten posterior fossa tumour cases with a panel of neurosurgery, neurology, oncology and neuropsychology specialists working in a multidisciplinary paediatric tumour treatment programme.

DISCUSSION AND CONCLUSION

We have demonstrated its use and hope that it may improve reliability between different assessors both in evaluating the outcomes of existing programmes and treatments as well as aiding in trials which may directly compare the effects of surgical and medical treatments.

摘要

引言

儿童后颅窝肿瘤手术后可能会出现并发症。尽管这些并发症可能会对儿童产生重大的长期行为和认知后果,但相关报告主观且不一致。这使得外科医生、治疗方案和治疗方法之间的比较存在问题。

材料与方法

我们设计了一种因果关系工具,基于用于评估药物不良反应的工具,通过一系列简单问题来评估手术后的不良事件是否可归类为手术并发症。这个我们称为“利物浦神经外科并发症因果关系评估工具”的工具,是通过与在多学科儿科肿瘤治疗项目中工作的神经外科、神经科、肿瘤科和神经心理学专家小组一起回顾一系列10例后颅窝肿瘤病例而开发的。

讨论与结论

我们展示了它的用途,并希望它可以提高不同评估者之间在评估现有治疗方案和治疗效果时的可靠性,同时也有助于直接比较手术和药物治疗效果的试验。

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