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Homeodomain-containing protein HOXB9 regulates expression of growth and angiogenic factors, facilitates tumor growth in vitro and is overexpressed in breast cancer tissue.
FEBS J. 2012 Oct;279(19):3715-3726. doi: 10.1111/j.1742-4658.2012.08733.x. Epub 2012 Aug 31.
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Mixed lineage leukaemia-4 regulates cell-cycle progression and cell viability and its depletion suppresses growth of xenografted tumour in vivo.
Br J Cancer. 2012 Jul 10;107(2):315-24. doi: 10.1038/bjc.2012.263. Epub 2012 Jun 19.
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HOXC10 is overexpressed in breast cancer and transcriptionally regulated by estrogen via involvement of histone methylases MLL3 and MLL4.
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The dynamic architecture of Hox gene clusters.
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HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.
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Fe(III)-salen and salphen complexes induce caspase activation and apoptosis in human cells.
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Homeotic proteins participate in the function of human-DNA replication origins.
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HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis.
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Mixed lineage leukemia histone methylases play critical roles in estrogen-mediated regulation of HOXC13.
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