Kumar M N, Honne T
Department of Prosthodontics, J.S.S. Dental College and Hospital, Karnataka, India.
Eur J Prosthodont Restor Dent. 2012 Dec;20(4):159-62.
To investigate the literature regarding the survival rate of dental implants in bisphosphonate users as compared to non-users. An online search of literatures through MEDLINE-PUBMED (1950-March 2012), Cochrane Database of Systematic reviews, the Cochrane Central Register of Controlled Trials (CENTRAL) (1800-March 2012) and EMBASE (1966-March 2012) databases was performed. All the relevant publications were identified and full texts of these articles were obtained. After scrutinizing the relevant articles and their related references five articles that fulfilled the inclusion criteria were finalized. Only one study stated that dental implant failure was higher in patients under bisphosphonate therapy. The implant survival rates ranged between 95% and 100% in case of bisphosphonate users and 96.5% to 99.2% in non-users. Within the limitations of this review, it can be concluded that short term bisphosphonate therapy does not increase or decrease the survival rate of dental implants in bisphosphonate users as compared to non-users.
旨在调查与未使用双膦酸盐类药物的患者相比，使用双膦酸盐类药物的患者种植牙的存活率相关文献。通过MEDLINE-PUBMED（1950年至2012年3月）、Cochrane系统评价数据库、Cochrane对照试验中心注册库（CENTRAL）（1800年至2012年3月）以及EMBASE（1966年至2012年3月）数据库对文献进行在线检索。识别出所有相关出版物并获取这些文章的全文。在仔细审查相关文章及其参考文献后，最终确定了五篇符合纳入标准的文章。只有一项研究表明接受双膦酸盐治疗的患者种植牙失败率更高。使用双膦酸盐类药物的患者种植牙存活率在95%至100%之间，未使用双膦酸盐类药物的患者存活率在96.5%至99.2%之间。在本综述的局限性范围内，可以得出结论，与未使用双膦酸盐类药物的患者相比，短期双膦酸盐治疗不会增加或降低使用双膦酸盐类药物的患者种植牙的存活率。
Zotero 插件