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隆突性皮肤纤维肉瘤的皮肤镜检查:15 例研究。

Dermoscopy of dermatofibrosarcoma protuberans: a study of 15 cases.

机构信息

Department of Dermatology, Lyon 1 University, Centre Hospitalier Lyon Sud, 69495, Pierre Bénite CEDEX, France.

出版信息

Br J Dermatol. 2013 Jul;169(1):85-90. doi: 10.1111/bjd.12318.

Abstract

BACKGROUND

Dermatofibrosarcoma protuberans (DFSP) is a rare malignant cutaneous tumour of which diagnosis is often delayed because of the lack of early clinical clues.

OBJECTIVES

To describe the main dermoscopic features of DFSP.

METHODS

We performed dermoscopic examination in 15 unselected, consecutive cases of biopsy-proven DFSP. Firstly, six dermoscopic features were identified collegially, then all cases were reviewed separately by six experienced dermoscopists. In a given lesion, features recognized only by all dermoscopists were taken into account.

RESULTS

The median number of dermoscopic features was four per lesion. The following dermoscopic features were found: delicate pigmented network (87%), vessels (80%), structureless light brown areas (73%), shiny white streaks (67%), pink background coloration (67%) and structureless hypo- or depigmented areas (60%). When detected, vessels were of arborizing type in 11 of 12 cases, and presented as either unfocused only, or both unfocused and focused.

CONCLUSIONS

This first study of the dermoscopic spectrum of DFSP identifies six dermoscopic features (often associated in a multicomponent pattern) and a peculiar vascular pattern. Whether dermoscopy can help to identify suspected DFSP remains to be established by further studies.

摘要

背景

隆突性皮肤纤维肉瘤(DFSP)是一种罕见的皮肤恶性肿瘤,由于缺乏早期临床线索,其诊断常常被延误。

目的

描述 DFSP 的主要皮肤镜特征。

方法

我们对 15 例未经选择的、经活检证实的 DFSP 连续病例进行了皮肤镜检查。首先,共同确定了 6 种皮肤镜特征,然后由 6 位有经验的皮肤镜医生分别对所有病例进行了回顾。在给定的病变中,仅被所有皮肤镜医生识别的特征被考虑在内。

结果

病变的中位数为 4 种皮肤镜特征。发现了以下皮肤镜特征:精细的色素网(87%)、血管(80%)、无结构的浅棕色区域(73%)、闪亮的白色条纹(67%)、粉红色的背景着色(67%)和无结构的色素减退或脱色素区域(60%)。在 12 例中,有 11 例检测到的血管呈树枝状,要么仅为无焦点,要么既有无焦点也有焦点。

结论

这是对 DFSP 皮肤镜谱的首次研究,确定了 6 种皮肤镜特征(通常以多成分模式相关联)和一种特殊的血管模式。皮肤镜检查是否有助于识别可疑的 DFSP,还需要进一步的研究来确定。

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