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马匹吸入麻醉剂。

Inhaled anesthetics in horses.

作者信息

Brosnan Robert J

机构信息

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.

出版信息

Vet Clin North Am Equine Pract. 2013 Apr;29(1):69-87. doi: 10.1016/j.cveq.2012.11.006. Epub 2013 Jan 18.

DOI:10.1016/j.cveq.2012.11.006
PMID:23498046
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3601575/
Abstract

Inhaled agents represent an important and useful class of drugs for equine anesthesia. This article reviews the ether-type anesthetics in contemporary use, their uptake and elimination, their mechanisms of action, and their desirable and undesirable effects in horses.

摘要

吸入性麻醉剂是马麻醉中一类重要且有用的药物。本文综述了当前使用的醚类麻醉剂、它们的摄取与消除、作用机制以及在马身上的有利和不利影响。

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本文引用的文献

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The confidential enquiry into perioperative equine fatalities (CEPEF): mortality results of Phases 1 and 2.围手术期马匹死亡情况保密调查(CEPEF):第1阶段和第2阶段的死亡率结果
Vet Anaesth Analg. 2002 Oct;29(4):159-170. doi: 10.1046/j.1467-2995.2002.00106.x. Epub 2016 Nov 15.
2
Increased NMDA receptor inhibition at an increased Sevoflurane MAC.在增加的七氟醚 MAC 下增加 NMDA 受体抑制。
BMC Anesthesiol. 2012 Jun 6;12:9. doi: 10.1186/1471-2253-12-9.
3
Effects of hypercapnic hyperpnea on recovery from isoflurane or sevoflurane anesthesia in horses.高碳酸血症性深呼吸对马从异氟烷或七氟烷麻醉中恢复的影响。
Vet Anaesth Analg. 2012 Jul;39(4):335-44. doi: 10.1111/j.1467-2995.2012.00727.x. Epub 2012 May 11.
4
Solubility of haloether anesthetics in human and animal blood.卤醚麻醉剂在人和动物血液中的溶解度。
Anesthesiology. 2012 Jul;117(1):48-55. doi: 10.1097/ALN.0b013e3182557cc9.
5
Inhibition of α5 γ-Aminobutyric acid type A receptors restores recognition memory after general anesthesia.α5 γ-氨基丁酸 A 型受体抑制作用可恢复全麻后识别记忆
Anesth Analg. 2012 Apr;114(4):845-55. doi: 10.1213/ANE.0b013e31824720da. Epub 2012 Mar 1.
6
Gamma-aminobutyric acid type A receptor β3 subunit forebrain-specific knockout mice are resistant to the amnestic effect of isoflurane.γ-氨基丁酸 A 型受体 β3 亚单位脑特异性敲除小鼠对异氟烷的遗忘效应有抗性。
Anesth Analg. 2011 Sep;113(3):500-4. doi: 10.1213/ANE.0b013e3182273aff. Epub 2011 Aug 3.
7
GABA(A) receptor antagonism increases NMDA receptor inhibition by isoflurane at a minimum alveolar concentration.在最低肺泡浓度时,γ-氨基丁酸A(GABA(A))受体拮抗作用会增强异氟烷对N-甲基-D-天冬氨酸(NMDA)受体的抑制作用。
Vet Anaesth Analg. 2011 May;38(3):231-9. doi: 10.1111/j.1467-2995.2011.00605.x.
8
Does anesthetic additivity imply a similar molecular mechanism of anesthetic action at N-methyl-D-aspartate receptors?麻醉药相加性是否意味着 N-甲基-D-天冬氨酸受体麻醉作用的分子机制相似?
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