Gnofam M, Muller D, Meriaux M, Carpentier S, Deruelle P
EA 4489, environnement périnatal et croissance, faculté de médecine Henri-Warembourg, université Lille 2, PRES Lille-Nord de France, 59045 Lille, France; Pôle d'obstétrique, maternité Jeanne-de-Flandre, CHRU de Lille, 1, rue Eugène-Avinée, 59037 Lille, France.
J Gynecol Obstet Biol Reprod (Paris). 2013 Nov;42(7):678-84. doi: 10.1016/j.jgyn.2013.01.008. Epub 2013 Mar 14.
In popular belief, a higher rate of premature rupture of membranes (PROM) might be associated with atmospheric pressure (AP) variations. Results of past studies are contradictory. We aimed to assess whether or not AP values influence the rate of PROM.
We performed a retrospective longitudinal study of women admitted for PROM from January 1st, 2009 to December 3rd, 2009. AP values for 2009 were obtained at the local meteorological station.
AP values (average, minimum and maximum) and its variations did not influence the rate of PROM for 341 patients included in the study, as well as in the group of 187 patients with a negative result of vaginal swab or amniotic fluid sample. After exclusion of premature PROM, mean AP variation the days before PROM was higher than AP variations of the days without PROM (6.3hPa IC95% [5.65-7.00] vs. 5.2 IC95% [4.70-5.79], P=0.029). No higher rate of occurrence of PROM was noticed during the days with low AP (AP less than average AP of the year equal to 1009hPa or AP less than normal AP equal to 1013.2hPa) or during the days with a high variability (maximal AP-minimal AP greater than 5hPa).
Our data did not support the hypothesis that AP influence the rate PROM.
在大众观念中，胎膜早破（PROM）发生率较高可能与大气压力（AP）变化有关。以往研究结果相互矛盾。我们旨在评估AP值是否会影响胎膜早破发生率。
我们对2009年1月1日至2009年12月3日因胎膜早破入院的女性进行了一项回顾性纵向研究。2009年的AP值取自当地气象站。
研究纳入的341例患者以及187例阴道拭子或羊水样本结果为阴性的患者中，AP值（平均值、最小值和最大值）及其变化均未影响胎膜早破发生率。排除早产性胎膜早破后，胎膜早破前几天的平均AP变化高于无胎膜早破日子的AP变化（6.3hPa，95%置信区间[5.65 - 7.00] 对比5.2，95%置信区间[4.70 - 5.79]，P = 0.029）。在AP较低的日子（AP低于该年平均AP值1009hPa或AP低于正常AP值1013.2hPa）或变化较大的日子（最大AP - 最小AP大于5hPa），未发现胎膜早破发生率更高。
我们的数据不支持AP影响胎膜早破发生率这一假说。
