Routhier Sonia, Gravel-Laflamme Karine, Macoir Joël
Département de réadaptation, Programme de maîtrise en orthophonie, Faculté de médecine, Université Laval, Québec, Canada, Centre de recherche, Institut universitaire en santé mentale, Québec, Canada.
Geriatr Psychol Neuropsychiatr Vieil. 2013 Mar;11(1):87-97. doi: 10.1684/pnv.2013.0395.
Primary progressive aphasia is a neurodegenerative condition characterised by a progressive and isolated disorder of expressive language, associated with atrophy of the left posterior frontoinsular region (nonfluent/agrammatic variant) or with atrophy of the left temporoparietal junction area (logopenic variant). This literature review reports studies about language therapies for these two variants of primary progressive aphasia. More precisely, the review presents the behavioral interventions and the augmentative/alternative communication tools reported in the literature to improve language performances or to compensate for language difficulties. Most of these studies reported that interventions are efficient. However, inconsistent results are found regarding maintenance of improvement and generalization to untreated language abilities. Other studies are still required to establish the clinical relevance of interventions for language and communication disorders in primary progressive aphasia. In these studies, the use of more ecological interventions focusing on the specific needs of people living with this disease should be specifically addressed.
原发性进行性失语是一种神经退行性疾病，其特征为进行性且孤立的表达性语言障碍，与左侧额岛叶后部区域萎缩（非流畅性/语法缺失型变体）或左侧颞顶叶交界处区域萎缩（语义性痴呆型变体）相关。这篇文献综述报告了关于原发性进行性失语这两种变体的语言治疗研究。更确切地说，该综述呈现了文献中报道的行为干预措施以及辅助/替代沟通工具，以改善语言表现或弥补语言困难。这些研究大多报告称干预措施是有效的。然而，在改善效果的维持以及向未治疗的语言能力的泛化方面，发现了不一致的结果。仍需要其他研究来确立针对原发性进行性失语中语言和沟通障碍的干预措施的临床相关性。在这些研究中，应特别关注使用更符合实际情境的干预措施，这些措施要关注患有这种疾病的人的特定需求。
