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初发劳力型心绞痛:初始特征及6至12个月随访结果

New-onset angina pectoris: initial characteristics and results of a 6 to 12-month follow-up.

作者信息

Ananich V A, Gratsianskii N A, Karasev A V, Olferiev A M, Nechaev A S, Yanus V M, Oganov R G

机构信息

Institute of Preventive Cardiology, USSR Cardiology Research Centre, Academy of Medical Sciences of USSR, Moscow.

出版信息

Cor Vasa. 1990;32(2):99-106.

PMID:2350972
Abstract

173 patients, aged 46.8 years on the average, were examined in the first 3 months after onset of angina pectoris. 97% of them presented at least one of risk factors (smoking, arterial hypertension, overweight, dyslipoproteinaemia), in 79% two or more risk factors were present simultaneously. A greater than 70% stenosis of one coronary artery was present in 51%, in 10% the stenosis was smaller than 70%, in 4% the coronary arteries were intact. In 131 patients without a history of myocardial infarction, vasospastic angina, overweight, and simultaneous presence of 3 or 4 risk factors occurred more frequently than in 42 patients with a history of myocardial infarction. In the first month, complications were registered only in patients with unstable angina pectoris (5 out of 41, i.e., 12%). During the later period of follow-up in 102 patients, complications occurred in 5% and complete clinical remission was registered in 35%. In patients with remission, positive exercise tests and haemodynamically significant stenoses of 2 or 3 coronary arteries were less frequently found on initial examination than in patients with sustained angina pectoris.

摘要

173例平均年龄为46.8岁的患者在心绞痛发作后的前3个月接受了检查。其中97%的患者存在至少一种危险因素(吸烟、动脉高血压、超重、血脂蛋白异常血症),79%的患者同时存在两种或更多危险因素。51%的患者存在一支冠状动脉狭窄超过70%,10%的患者狭窄小于70%,4%的患者冠状动脉完好无损。在131例无心肌梗死病史的患者中,血管痉挛性心绞痛、超重以及同时存在3种或4种危险因素的情况比42例有心肌梗死病史的患者更为常见。在第一个月,仅在不稳定型心绞痛患者中出现并发症(41例中有5例,即12%)。在随后的随访期内,102例患者中有5%出现并发症,35%实现了完全临床缓解。在缓解的患者中,与持续性心绞痛患者相比,初始检查时运动试验阳性以及2支或3支冠状动脉存在血流动力学显著狭窄的情况较少见。

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