Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Faculty of Pharmacy and Medicine, Urology Unit ICOT, Latina, Italy.
J Endourol. 2013 Aug;27(8):989-93. doi: 10.1089/end.2013.0033. Epub 2013 May 23.
Surgical treatment of patients with prostate cancer currently involves laparoscopic radical prostatectomy (LRP) or robot-assisted LRP. Continence and nerve-sparing procedures in these techniques are supported by dissection and hemostatic surgical devices powered by different types of energy. The aim of this study was to assess recovery of continence and erectile function after laparoscopic extraperitoneal radical prostatectomy comparing two surgical devices for dissection and hemostasis-radiofrequency (RF) and ultrasound (US) scalpels.
A total of 132 men with localized prostate cancer were prospectively enrolled and scheduled for extraperitoneal LRP. Patients were randomly assigned to the RF group (LigaSure; n=66) or the US group (UltraCision; n=66). Outcomes were measured by the self-administered questionnaires (International Consultation on Incontinence Questionnaire-Urinary Incontinence [ICIQ-UI] and International Index of Erectile Function 5 [IIEF 5]) 15 days before surgery, 90 and 180 days after prostatectomy to assess recovery of urinary continence and erectile function.
No significant difference was found between the two groups regarding operative time, intra- and perioperative complications, or time of hospital stay. At 180 days after surgery, patients in the RF-treated group showed better recovery in terms of continence and erectile function compared with patients in the US group (ICIQ-UI: p=0.0016; IIEF 5: p=0.0352).
The use of the RF scalpel provided better functional outcomes compared with the US scalpel in patients undergoing extraperitoneal LRP. This might be attributed to the low contiguous damage of those tissues, which are not directly involved in dissection and hemostasis, achieved using the RF device.
目前,前列腺癌患者的外科治疗包括腹腔镜根治性前列腺切除术(LRP)或机器人辅助 LRP。这些技术中的控尿和神经保护手术是通过使用不同类型能量驱动的解剖和止血外科器械来支持的。本研究的目的是评估比较两种用于解剖和止血的外科器械(射频[RF]和超声[US]手术刀)的腹腔镜经腹膜外根治性前列腺切除术患者术后控尿和勃起功能的恢复情况。
共有 132 名局限性前列腺癌患者前瞻性入组并计划接受经腹膜外 LRP。患者被随机分配到 RF 组(LigaSure;n=66)或 US 组(UltraCision;n=66)。通过患者自行填写的问卷(国际尿失禁咨询问卷-尿失禁部分[ICIQ-UI]和国际勃起功能指数 5 分[IIEF 5])在术前 15 天、前列腺切除术后 90 天和 180 天评估尿控和勃起功能的恢复情况。
两组之间在手术时间、围手术期并发症或住院时间方面无显著差异。在手术后 180 天,RF 治疗组的患者在控尿和勃起功能方面的恢复情况明显优于 US 治疗组(ICIQ-UI:p=0.0016;IIEF 5:p=0.0352)。
与 US 手术刀相比,在接受经腹膜外 LRP 的患者中,使用 RF 手术刀可获得更好的功能结果。这可能归因于 RF 装置可实现对那些不直接参与解剖和止血的组织的低连续损伤。