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采用区域性腰围切点诊断代谢综合征在西班牙的流行情况:di@bet.es 研究。

Prevalence of the metabolic syndrome in Spain using regional cutoff points for waist circumference: the di@bet.es study.

机构信息

Department of Endocrinology and Nutrition, Madrid, Spain.

出版信息

Acta Diabetol. 2013 Aug;50(4):615-23. doi: 10.1007/s00592-013-0468-8. Epub 2013 Mar 20.

Abstract

The aim of the study is to assess the prevalence of metabolic syndrome (MetS) in Spain using specific cutoff points for waist circumference (WC) (>94.5 cm for men and >89.5 cm for women) and evaluating the influence of several socio-demographic and economic factors. Data on MetS were obtained from a national study of 4,727 subjects from 18 to 90 years of age, conducted in Spain between 2009 and 2010 (The di@bet.es study). MetS was defined applying the new Harmonized definition (evaluating the use of abdominal obesity (AO) as a obligatory criterion for MetS or not) as well as with other widely used criteria. Results were then compared with data from previous studies. Multiple logistic regression models were used to evaluate the influence of different social factors. The age-standardized MetS prevalence was 38.37 % (CI 35.74-40.99) in men and 29.62 % (CI 27.56-31.69) in women, when AO was required as a diagnostic criterion; 42.13 % (CI 39.37-44.89) and 32.31 % (CI 30.15-34.47) in men and women, respectively, if AO was not considered mandatory. Prevalence of MetS increased with age (p < 0.001 for trend). Women with a lower educational level were more likely to have MetS (OR 4.4; 95 % CI: 2.84-6.7) as compared with those with a higher educational level. Subjects with MetS had a worse physical quality of life. The combination of AO, hypertension and carbohydrate alterations was the most common MetS' pattern. A high prevalence of MetS was detected in the Spanish population especially in men, the elderly and women with a low educational level.

摘要

本研究旨在使用特定的腰围(WC)切点(男性>94.5cm,女性>89.5cm)评估西班牙代谢综合征(MetS)的流行率,并评估多种社会人口和经济因素的影响。MetS 数据来自于西班牙 2009 年至 2010 年进行的一项全国性研究,该研究共纳入了 4727 名年龄在 18 至 90 岁的受试者(The di@bet.es 研究)。采用新的协调定义(评估腹部肥胖(AO)作为 MetS 的必需标准的使用与否)以及其他广泛使用的标准来定义 MetS。然后将结果与以前的研究数据进行比较。使用多因素逻辑回归模型评估不同社会因素的影响。当 AO 作为诊断标准时,男性和女性的年龄标准化 MetS 患病率分别为 38.37%(95%CI 35.74-40.99)和 29.62%(95%CI 27.56-31.69);如果不考虑 AO 为必需标准,男性和女性的 MetS 患病率分别为 42.13%(95%CI 39.37-44.89)和 32.31%(95%CI 30.15-34.47)。MetS 的患病率随年龄增长而增加(趋势 P<0.001)。与受教育程度较高的人相比,受教育程度较低的女性更容易发生 MetS(OR 4.4;95%CI:2.84-6.7)。患有 MetS 的患者的身体生活质量更差。AO、高血压和碳水化合物改变的组合是最常见的 MetS 模式。西班牙人群中 MetS 的患病率较高,尤其是男性、老年人和受教育程度较低的女性。

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