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利奈唑胺所致血清素综合征。

Linezolid-induced serotonin syndrome.

作者信息

Gupta Vishal, Karnik Niteen D, Deshpande Rushikesh, Patil Meenakshi Amit

机构信息

Department of Medicine, Seth G Medical College and KEM Hospital, Mumbai, Maharashtra, India.

出版信息

BMJ Case Rep. 2013 Mar 18;2013:bcr2012008199. doi: 10.1136/bcr-2012-008199.

DOI:10.1136/bcr-2012-008199
PMID:23513014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3618736/
Abstract

A young drug abuser was admitted to our intensive care unit for organophosphorus poisoning. He required mechanical ventilation and was started empirically on linezolid for suspected nosocomial infection. The patient developed high-grade fever with altered sensorium and clonus. Serotonin syndrome was suspected and the patient was started on cyproheptadine. He recovered within 3 days of withdrawing linezolide and administering cyproheptadine.

摘要

一名年轻的药物滥用者因有机磷中毒入住我们的重症监护病房。他需要机械通气,并因怀疑医院感染而经验性地开始使用利奈唑胺。患者出现高热、意识改变和阵挛。怀疑为血清素综合征,于是给患者开始使用赛庚啶。在停用利奈唑胺并给予赛庚啶后3天内,他康复了。

相似文献

1
Linezolid-induced serotonin syndrome.利奈唑胺所致血清素综合征。
BMJ Case Rep. 2013 Mar 18;2013:bcr2012008199. doi: 10.1136/bcr-2012-008199.
2
[Serotonin syndrome associated with linezolid].[与利奈唑胺相关的血清素综合征]
Med Clin (Barc). 2009 Feb 7;132(4):157-8. doi: 10.1016/j.medcli.2008.09.007. Epub 2008 Dec 3.
3
Serotonin syndrome and linezolid.血清素综合征与利奈唑胺
Clin Infect Dis. 2002 Jun 15;34(12):1651-2. doi: 10.1086/340710. Epub 2002 May 23.
4
Linezolid and serotonin syndrome.利奈唑胺与5-羟色胺综合征
Psychosomatics. 2001 Sep-Oct;42(5):432-4. doi: 10.1176/appi.psy.42.5.432.
5
Mild serotonin syndrome associated with concurrent linezolid and fluoxetine.与利奈唑胺和氟西汀同时使用相关的轻度血清素综合征。
Am J Health Syst Pharm. 2007 Jan 1;64(1):59-62. doi: 10.2146/ajhp060227.
6
[Serotonergic syndrome in combination of linezolid (Zyvixid) and SSRI].利奈唑胺(斯沃)与选择性5-羟色胺再摄取抑制剂联用所致的5-羟色胺综合征
Lakartidningen. 2009;106(44):2856.
7
Serotonin syndrome and linezolid.血清素综合征与利奈唑胺
J Am Acad Child Adolesc Psychiatry. 2004 Jul;43(7):790. doi: 10.1097/01.chi.0000128830.13997.aa.
8
Serotonin syndrome precipitated by the monoamine oxidase inhibitor linezolid.由单胺氧化酶抑制剂利奈唑胺引发的血清素综合征。
Am J Psychiatry. 2007 Feb;164(2):346-7. doi: 10.1176/ajp.2007.164.2.346b.
9
Serotonin syndrome as a consequence of drug-resistant infections: an interaction between linezolid and citalopram.作为耐药性感染后果的血清素综合征:利奈唑胺与西酞普兰之间的相互作用。
J Am Med Dir Assoc. 2004 Mar-Apr;5(2):111-3. doi: 10.1097/01.JAM.0000110645.20530.46.
10
[Likely serotoninergic syndrome from an interaction between amitryptiline, paroxetine, and linezolid].[由阿米替林、帕罗西汀和利奈唑胺相互作用引发的可能的血清素能综合征]
Farm Hosp. 2005 Jul-Aug;29(4):292-3.

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Neuroleptic malignant syndrome and serotonin syndrome: a comparative bibliometric analysis.神经阻滞剂恶性综合征和血清素综合征:一项比较文献计量分析。
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Management of severe arterial hypertension associated with serotonin syndrome: a case report analysis based on systematic review techniques.与血清素综合征相关的重度动脉高血压的管理:基于系统评价技术的病例报告分析
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Prevention, recognition, and management of serotonin syndrome.预防、识别和治疗血清素综合征。
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Serotonin toxicity associated with the use of linezolid: a review of postmarketing data.与利奈唑胺使用相关的血清素毒性:上市后数据综述。
Clin Infect Dis. 2006 Jun 1;42(11):1578-83. doi: 10.1086/503839. Epub 2006 Apr 27.
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2004 Annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System.美国毒物控制中心协会毒物暴露监测系统2004年年报。
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