一例血清阴性灾难性抗磷脂抗体综合征病例。

A case of seronegative catastrophic antiphospholipid antibody syndrome.

作者信息

Shreders Amanda, Bar Michael

机构信息

Stamford Hospital/Columbia University, College of Physicians and Surgeons, 30 Shelburne Road, Stamford, CT 06904, USA.

出版信息

Conn Med. 2013 Feb;77(2):81-3.

PMID:23513635

Abstract

Catastrophic antiphospholipid antibody syndrome (CAPS) is a rare syndrome associated with multiorgan failure that carries a high mortality rate. It has been defined previously by the presence of autoantibodies in a patient with acute multiorgan failure as a result of small vessel occlusion by multiple thrombi. We report a patient who meets all criteria of CAPS except for persistent seronegativity.

摘要

灾难性抗磷脂抗体综合征（CAPS）是一种与多器官功能衰竭相关的罕见综合征，死亡率很高。先前它被定义为因多个血栓导致小血管闭塞而出现急性多器官功能衰竭的患者体内存在自身抗体。我们报告了一名除持续血清学阴性外符合CAPS所有标准的患者。