Ito Y, Mizutani S, Nomura S, Kurauchi O, Kasugai M, Narita O, Tomoda Y
Department of Obstetrics and Gynecology, Nagoya University School of Medicine, Japan.
Horm Metab Res. 1990 Apr;22(4):252-5. doi: 10.1055/s-2007-1004895.
Serum kininase I activity was measured in normal pregnancy and pre-eclampsia. The mean value in nonpregnant controls was 180 +/- 25 (SD) nmol/min/ml. Kininase I activity during normal pregnancy significantly increased after week 14, reaching the highest value (240 +/- 20 nmol/min/ml) at weeks 38 and 40. The kininase I activity in pregnancy complicated by severe pre-eclampsia was higher than that in normal pregnancy. The possible role played by elevated kininase I levels in pre-eclampsia was discussed.
在正常妊娠和先兆子痫中测量了血清激肽酶I活性。未怀孕对照组的平均值为180±25（标准差）nmol/分钟/毫升。正常妊娠期间，激肽酶I活性在孕14周后显著增加，在孕38周和40周时达到最高值（240±20 nmol/分钟/毫升）。合并严重先兆子痫的妊娠中激肽酶I活性高于正常妊娠。讨论了先兆子痫中激肽酶I水平升高可能发挥的作用。
